Evidence map›Paper›PMID 36112219›Full record

Observational studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Effect of external eyelid weighting on eyelid and eyebrow position in normal and ptosis patients.

Alexandra I Manta, Nicholas J Jackson, Joshua Dan, Annie Tran, Daniel B Rootman

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alexandra I MantaDivision of Orbital and Ophthalmic Plastic Surgery, Jules Stein Eye Institute, University of California, 300 Stein Plaza UCLA, Los Angeles, CA, 9009, USA. alexandramanta@yahoo.com.
Nicholas J JacksonDavid Geffen School of Medicine, Department of Medicine Statistics Core, University of California, Los Angeles, Los Angeles, USA.
Joshua DanDivision of Orbital and Ophthalmic Plastic Surgery, Jules Stein Eye Institute, University of California, 300 Stein Plaza UCLA, Los Angeles, CA, 9009, USA.
Annie TranDivision of Orbital and Ophthalmic Plastic Surgery, Jules Stein Eye Institute, University of California, 300 Stein Plaza UCLA, Los Angeles, CA, 9009, USA.
Daniel B RootmanDivision of Orbital and Ophthalmic Plastic Surgery, Jules Stein Eye Institute, University of California, 300 Stein Plaza UCLA, Los Angeles, CA, 9009, USA.
Doheny Eye Institute · USUniversity of California, Los Angeles · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
NIH/ National Centre for Advanced Translational Science UL1TR001881
6 · The paper itself

Abstract

purposeThis study aims to characterize the physiologic response of both eyelid and eyebrow position to increasing downward forces simulated by external weights.

methodsIn this prospective observational study, both normal individuals and patients affected by ptosis were tested. External eyelid weights were placed on one upper eyelid with incrementally increasing weight from 0.2 to 2.4 g. The eyelid carrying the weight was randomly selected for normal subjects and patients with bilateral ptosis, whereas for unilateral ptosis, the ptotic eyelid was utilized. Photographs were obtained at baseline and with increasing weight until MRD1 reached 0 on the weighted side or, until 2.4 g was reached. Eyelid and brow position on the weighted and unweighted sides were digitally measured in millimeter. Primary outcome measures were change in the margin to reflex distance (MRD1) and pupil to brow distance (PTB) with weight on the weighted and unweighted sides for normal and ptosis subjects.

resultsThe weighted eyelid MRD1 decreased linearly with increasing weight. This was true for normal and ptosis subjects. The unweighted eyelid MRD1 increased linearly with increasing weight. This was also the case for both normal and ptosis subjects. With increasing weight, PTB increased linearly on the weighted side. No significant intergroup differences were noted.

conclusionsIn normal and ptosis subjects, when external weight on the eyelid is incrementally increased, the weighted eyelid MRD1 decreases, the unweighted eyelid MRD1 increases, and both brows elevate in a linear fashion.

Indexed as

BlepharoplastyBlepharoptosisEyebrowsEyelidsHumansProspective StudiesPupilRetrospective StudiesBlepharoptosisBrowEyelid physiologyEyelid weightPtosisUpper eyelid

Identifiers

PMID36112219
OpenAlexW4296027810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.