ArticleRheumatology international2022
Efficacy and safety of a mobile app intervention in patients with inflammatory arthritis: a prospective pilot study.
Article in Rheumatology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- [Medical health apps for psoriasis and psoriatic arthritis].Zeitschrift fur Rheumatologie · 2025Pooled it
- Trial
- Digital physical-activity engagement and 12-week patient-reported outcomes in inflammatory arthritis: a retrospective real-world cohort study.Clinical rheumatology · 2026Article
- Clinical-psychosocial archetypes predict short-term outcomes in inflammatory arthritis: an unsupervised segmentation study.Clinical rheumatology · 2026Observational
- Article
- Baseline pain, fatigue, and sleep quality predict 12-week pain improvement in inflammatory arthritis: retrospective real-world analysis of a digital health application cohort.Rheumatology international · 2026Article
- An Intelligent Interactive Management Platform for Rheumatoid Arthritis Care: Real-World Observational Study.JMIR medical informatics · 2026Observational
- Predictors of adherence to a digital health application in patients with inflammatory arthritis: retrospective analysis.Rheumatology international · 2025Article
- Professional-Facing Digital Health Technology for the Care of Patients With Chronic Pain: Scoping Review.Journal of medical Internet research · 2025Article
- Exploring the Physical Activity Counselling for Patients With Rheumatoid Arthritis-Perceptions of Nurses and Physiotherapists.Musculoskeletal care · 2025Article
- Patients' Experienced Usability and Satisfaction With Digital Health Solutions in a Home Setting: Instrument Validation Study.JMIR medical informatics · 2025Article
- Digital Multidomain Lifestyle Intervention for Community-Dwelling Older Adults: A Mixed Methods Evaluation.International journal of public health · 2025Article
- [Digital health applications-What we should know as rheumatologists].Zeitschrift fur Rheumatologie · 2024Review
- Digital Health and Self-Management in Idiopathic Inflammatory Myopathies: A Missed Opportunity?Current rheumatology reports · 2024Review
- Efficacy of a cognitive-behavioral digital therapeutic on psychosocial outcomes in rheumatoid arthritis: randomized controlled trial.Npj mental health research · 2024Article
- Evidence for telemedicine heterogeneity in rheumatic and musculoskeletal diseases care: a scoping review.Clinical rheumatology · 2024Article
- The exercise-app Axia for axial spondyloarthritis enhances the home-based exercise frequency in axial spondyloarthritis patients - A cross-sectional survey.Rheumatology international · 2024Article
- Digital Therapeutics for Improving Effectiveness of Pharmaceutical Drugs and Biological Products: Preclinical and Clinical Studies Supporting Development of Drug + Digital Combination Therapies for Chronic Diseases.Journal of clinical medicine · 2024Review
- Disease activity and fatigue in inflammatory arthritis patients with different dietary preferences: a retrospective exploratory cross-sectional study.Reumatologia · 2024Article
- Recommendation to implementation of remote patient monitoring in rheumatology: lessons learned and barriers to take.RMD open · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
EULAR highlighted the essential role of digital health in increasing self-management and improving clinical outcomes in patients with arthritis. The objective of this study was to evaluate the efficacy and safety of the digital health application (DHA) in patients with inflammatory arthritis. We assessed demographic parameters, treatment regimen, disease activity, and other patient-reported outcomes at baseline and after 4 weeks of DHA use added to standard care treatment. Of 17 patients, who completed the study, 7 (41.2%) patients were male, ranging from 19 to 63 (40.5 ± 12.2) years. No significant change in antirheumatic treatment was observed during the study. Statistically significant improvements (p < 0.05) were noted for health-related quality of life (increase in Physical Component Summary of Short Form-36 (SF-36) by 23.6%) and disease activity (decrease of Clinical Disease Activity Index and Simple Disease Activity Index by 38.4% and 39.9%, respectively). Clinically significant improvement was demonstrated for SF-36 Total Score (+ 14.4%), disease activity (Rheumatoid Arthritis Disease Activity Index- 5 to 15.9%), and depression (Patient Health Questionnaire- 9 to 13.5%). None of the efficacy parameters showed negative trends. No adverse events were reported throughout the study. The usability level was high i.e., the mean mHealth Application Usability Questionnaire Score of 5.96 (max.: 7.0) demonstrated a high level of application usability. This suggests that using a personalized disease management program based on DHA significantly improves several measures of patient-reported outcomes and disease activity in patients with inflammatory arthritis in a timely manner. These findings highlight the potential of complementary digital therapy in patients with inflammatory arthritis.
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