Evidence map›Paper›PMID 36112184›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2022

Percutaneous treatment options for acute pulmonary embolism: a clinical consensus statement by the ESC Working Group on Pulmonary Circulation and Right Ventricular Function and the European Association of Percutaneous Cardiovascular Interventions.

Piotr Pruszczyk, Frederikus A Klok, Nils Kucher, Marek Roik, Nicolas Meneveau, Andrew S P Sharp, Jens Erik Nielsen-Kudsk, Slobodan Obradović, Stefano Barco, Francesco Giannini and 4 more

Abstract readConsensus Statement
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
123citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

123 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. When Size Matters: Advanced Treatment of Acute Pulmonary Embolism Caused by a Large Snake-Like Thrombus.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  8. Article
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  11. Catheter Thrombectomy of Massive Pulmonary Embolism Secondary to Spongostan Embolisation: A Case Report.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  12. Article
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  19. Procedure-Related Mortality in Aspiration Thrombectomy for Pulmonary Embolism: A MAUDE Database Analysis of the Inari FlowTriever and Penumbra Indigo Systems.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2026
    Article
  20. Article

63 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Piotr PruszczykDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Frederikus A KlokDepartment of Medicine - Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands.
Nils KucherDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.
Marek RoikDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Nicolas MeneveauHôpital Jean Minjoz, Besançon, France and University of Burgundy Franche-Comté, Besançon, France.
Andrew S P SharpUniversity Hospital of Wales, Cardiff, UK and University of Exeter, Exeter, UK.
Jens Erik Nielsen-KudskDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Slobodan ObradovićClinic of Cardiology, Military Medical Academy, School of Medicine, University of Defence, Belgrade, Serbia.
Stefano BarcoCenter for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
Francesco GianniniInterventional Cardiology Unit, GVM Care and Research, Maria Cecilia Hospital, Cotignola, Italy.
Giulio StefaniniDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
Giuseppe TarantiniDepartment of Cardiac, Thoracic, and Vascular Sciences and Public Health, University of Padova, Policlinico Universitario, Padova, Italy.
Stavros KonstantinidesCenter for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.
Dariusz DudekInterventional Cardiology Unit, GVM Care and Research, Maria Cecilia Hospital, Cotignola, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a growing clinical and scientific interest in catheter-directed therapy (CDT) of acute pulmonary embolism (PE). Currently, CDT should be considered for patients with high-risk PE, in whom thrombolysis is contraindicated or has failed. Also, CDT is a treatment option for initially stable patients in whom anticoagulant treatment fails, i.e., those who experience haemodynamic deterioration despite adequately dosed anticoagulation. However, the definition of treatment failure (primary reperfusion therapy or anticoagulation alone) remains an important area of uncertainty. Moreover, several techniques for CDT are available without evidence supporting one over the other, and variation in practice with regard to periprocedural anticoagulation is considerable. The aim of this position paper is to describe the currently available CDT approaches in PE patients and to standardise patient selection, the timing and technique of the procedure itself as well as anticoagulation regimens during CDT. We discuss several clinical scenarios of the clinical evaluation of the "efficacy" of thrombolysis and anticoagulation, including treatment failure with haemodynamic deterioration and treatment failure based on a lack of improvement. This clinical consensus statement serves as a practical guide for CDT, complementary to the formal guidelines.

Indexed as

Pulmonary EmbolismThrombolytic TherapyAcute DiseaseAnticoagulantsFibrinolytic AgentsHumansPulmonary CirculationTreatment OutcomeVentricular Function, RightAnticoagulantsFibrinolytic Agents

Identifiers

PMID36112184
PMCPMC10241264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.