ArticleHuman reproduction (Oxford, England)2022
Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology.
Registry-linked trialAbstract read
In one paragraph
Article in Human reproduction (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06188936 (Home Semen Analysis Tests As a Screening Tool for the Initial Assessment of Patients Referred to the Fertility Clinic), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Home Semen Analysis Tests As a Screening Tool for the Initial Assessment of Patients Referred to the Fertility Clinic: Assessing the Feasibility of a Randomised Trial in the UK
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effect of Endurance Exercise on Semen Quality in Male Athletes: A Systematic Review.Sports medicine - open · 2024Pooled it
- Heat exposure during susceptible windows of spermatogenesis and sperm epigenetic age.Human reproduction (Oxford, England) · 2026Trial
- Body fat percentage in relation to semen characteristics, testicular volume, and reproductive hormones: a cross-sectional study.Human reproduction (Oxford, England) · 2026Article
- Effectiveness of short-term, high-intensive, WHO laboratory standard-based training in sperm morphology assessment: evidence from a national program in China.Asian journal of andrology · 2026Article
- Double-stranded sperm DNA fragmentation measured with neutral comet assay as a predictor of IVF outcomes: evidence from three European clinics in a multi-centred prospective study.Human reproduction (Oxford, England) · 2026Article
- ABO blood group distribution and infertility risk in Southern China: a retrospective analysis of the Ganzhou Region.Journal of assisted reproduction and genetics · 2026Article
- An Artificial Intelligence-Based Computer Vision Model for Human Sperm Concentration, Motility, and Kinematics Analysis.Smart medicine · 2026Article
- Immunological mechanisms and precision stratification in male infertility: from testicular immune privilege and danger signal amplification to seminal immune biomarkers and mechanism-tailored intervention.Frontiers in immunology · 2026Review
- The impact of vasectomy on the seminal microbiome: possible implications and source of microbes.Human reproduction open · 2026Article
- Exploring geographical differences in semen quality of young men using spatial dependence analysis.Human reproduction (Oxford, England) · 2025Article
- Still counting sperm? Why novel, truly informative measurements of testis function in male infertility are urgently needed.Endocrine · 2025Review
- Article
- The sperm quality change in 6 months recovery from COVID-19: a retrospective observational study.Scientific reports · 2025Observational
- Fine particulate matter exposure and sperm DNA fragmentation in US men: a spatial cross-sectional study.Human reproduction (Oxford, England) · 2025Article
- Investigations on semen analysis capabilities and quality control measures in laboratories with different management modes.Journal of assisted reproduction and genetics · 2025Article
- Treatment with isotretinoin can improve de novo sperm production in nonobstructive azoospermia or cryptozoospermia.Journal of assisted reproduction and genetics · 2025Article
- Use of a sperm morphology assessment standardisation training tool improves the accuracy of novice sperm morphologists.Scientific reports · 2025Article
- Human sperm as an in vitro toxicity model: a versatile tool for assessing the risk of environmental contaminants.Archives of toxicology · 2025Article
- Normozoospermic infertile men possess subpopulations of sperm varying in DNA accessibility, relating to differing reproductive outcomes.Human reproduction (Oxford, England) · 2025Article
- Altered Endothelin Receptor Expression in Idiopathic Male Infertility: A Potential Therapeutic Target.Urology research & practice · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
87 authors.
Lars BjörndahlANOVA, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-4709-5807
Christopher L R BarrattReproductive Medicine Research Group, Division of Systems Medicine, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.ORCID 0000-0003-0062-9979
David MortimerOozoa Biomedical Inc., West Vancouver, BC, Canada.ORCID 0000-0002-0638-2893
Ashok AgarwalCase Western Reserve University, Moreland Hills, OH, USA.ORCID 0000-0003-0585-1026
Robert J AitkenPriority Research Centre for Reproductive Science, Faculty of Science and Faculty of Health & Medicine, University of Newcastle, Callaghan, NSW, Australia.ORCID 0000-0002-9152-156X
Juan G AlvarezCentro Androgen, La Coruña, Spain.ORCID 0000-0002-4851-9579
Natalie Aneck-HahnDepartment of Urology, University of Pretoria, Pretoria, South Africa.ORCID 0000-0002-3649-8889
Stefan ArverANOVA, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-2925-355X
Elisabetta BaldiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Tuscany, Italia.ORCID 0000-0003-1808-3097
Lluís BassasAndrology Department, Laboratory of Andrology and Sperm Bank, Fundació Puigvert, Barcelona, Spain.ORCID 0000-0002-3473-3611
Florence BoitrelleDepartment of Reproductive Biology, Fertility Preservation, Andrology, CECOS, Poissy Hospital, Poissy, France.ORCID 0000-0002-5322-0141
Riana BornmanSchool of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.ORCID 0000-0003-3975-2333
Douglas T CarrellAndrology and IVF Laboratory, Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID 0000-0002-6471-2803
José A CastillaGAMETIA Biobank, Granada, Spain.ORCID 0000-0003-2185-565X
Gerardo Cerezo ParraLAFER Sperm Bank, Tuxpan 10-606, Roma Sur, C.P. 06760, Cuauhtémoc, Mexico City, Mexico.ORCID 0000-0003-4577-159X
Jerome H CheckRobert Wood Johnson Medical School at Camden, The University of Medicine and Dentistry of New Jersey, Camden, NJ, USA.ORCID 0000-0002-2351-4595
Patricia S CuasnicuInstituto de Biología y Medicina Experimental (IbyME-CONICET), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0002-4784-488X
Sally Perreault DarneyUS EPA, Cary, NC, USA.ORCID 0000-0002-0315-1774
Christiaan de JagerFaculty of Health Science, University of Pretoria, Pretoria, South Africa.ORCID 0000-0002-3743-1715
Christopher J De JongeUniversity of Minnesota Medical Center, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-4083-5833
Joël R DrevetUniversité Clermont Auvergne/CNRS/INSERM-GreD Institute, Clermont-Ferrand, France.ORCID 0000-0003-3077-6558
Erma Z DrobnisSchool of Medicine, University of Missouri, Columbia, MI, USA.ORCID 0000-0001-5495-3489
Stefan S Du PlessisCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.ORCID 0000-0003-4617-4367
Michael L EisenbergMale Reproductive Medicine and Surgery, Stanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0001-5482-0141
Sandro C EstevesANDROFERT, Andrology and Human Reproduction Clinic, Campinas, Brazil.ORCID 0000-0002-1313-9680
Evangelini A EvgeniCRYOGONIA Cryopreservation Bank, Athens, Greece.ORCID 0000-0002-3909-9170
Alberto FerlinUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, Padova, Italia.ORCID 0000-0001-5817-8141
Nicolas GarridoIVI Foundation, Health Research Institute La Fe, Valencia, Spain.ORCID 0000-0001-8271-5218
Aleksander GiwercmanDepartment of Translational Medicine, Lund University, Malmö, Sweden.ORCID 0000-0001-5816-0785
Ilse G F GoovaertsAntwerp University Hospital, Edegem, Belgium.ORCID 0000-0002-3563-8499
Trine B HaugenDepartment of Life Sciences and Health, Oslo Metropolitan University, Oslo, Norway.ORCID 0000-0002-8814-3393
Ralf HenkelDepartment of Metabolism, Digestion & Reproduction, Imperial College London, London, UK.ORCID 0000-0003-1128-2982
Lars HenningsohnDivision of Urology, Department of CLINTEC, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-5521-8934
Marie-Claude HofmannDepartment of Endocrine Neoplasia & Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-4899-8039
James M HotalingDivision of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA.ORCID 0000-0002-4401-4565
Piotr JedrzejczakDepartment of Cell Biology, Poznan University of Medical Science, Poznan, Poland.ORCID 0000-0003-2437-7737
Pierre JouannetUniversité Paris Descartes, Paris, France.ORCID 0000-0003-1827-8986
Niels JørgensenDepartment of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0003-4827-0838
Jackson C Kirkman BrownCentre for Human Reproductive Science (ChRS), UK.ORCID 0000-0003-2833-8970
Csilla KrauszDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Florence, Italy.ORCID 0000-0001-6748-8918
Maciej KurpiszDepartment of Reproductive Biology and Stem Cells, Institutet of Human Genetics, Poznan, Poland.ORCID 0000-0003-3275-3245
Ulrik KvistANOVA, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-7874-3427
Dolores J LambBrady Department of Urology, Center for Reproductive Genomics and Englander Institute for Precision Medicine, Weill Cornell Medical College, Cornell University, New York, NY, USA.ORCID 0000-0002-4389-5065
Hagai LevineBraun School of Public Health and Community Medicine, Hadassah Medical Center, The Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0002-5597-4916
Kate L LovelandHudson Institute, Centre for Reproductive Health, Monash University, Clayton, VIC, Australia.ORCID 0000-0002-5750-8046
Robert I McLachlanHudson Institute of Medical Research, Centre for Endocrinology and Metabolism, Monash University, Clayton, VIC, Australia.ORCID 0000-0003-4637-3876
Ali MahranDermatology and Andrology Department, Assiut University Hospital, Assiut, Egypt.ORCID 0000-0001-7870-4110
Liana MareeDepartment of Medical Bioscience, University of the Western Cape, Bellville, South Africa.ORCID 0000-0003-4147-4221
Sarah Martins da SilvaReproductive Medicine Research Group, Division of Systems Medicine, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.ORCID 0000-0003-2579-4866
Michael T MbizvoCountry Director, Population Council (International Programs).ORCID 0000-0001-8262-8640
Andreas MeinhardtDepartment of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Giessen, Germany.ORCID 0000-0003-3711-2746
Roelof MenkveldDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.ORCID 0000-0002-2539-6852
Sharon T MortimerOozoa Biomedical Inc., West Vancouver, BC, Canada.ORCID 0000-0002-3498-5667
Sergey MoskovtsevDepartment of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-1303-6048
Charles H MullerMale Fertility Laboratory, Department of Urology, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0003-1593-2073
Maria José MunuceLaboratorio de Medicina Reproductiva, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina.ORCID 0000-0001-6919-7698
Monica MuratoriDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Florence, Italy.ORCID 0000-0003-0925-0009
Craig NiederbergerDepartment of Urology, UIC College of Medicine, IL, USA.ORCID 0000-0003-1691-7289
Cristian O'FlahertyDepartment of Surgery (Urology Division), McGill University, Montréal, QC, Canada.ORCID 0000-0001-8884-1274
Rafael OlivaMolecular Biology of Reproduction and Development Group, Biomedical Research Institute August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.ORCID 0000-0003-4876-2410
Willem OmbeletGenk Institute for Fertility Technology, Genk, Belgium.ORCID 0000-0002-7206-1537
Allan A PaceyDepartment of Oncology and Metabolism, University of Sheffield, Sheffield, UK.ORCID 0000-0002-4387-8871
Michael A PalladinoBloomfield College, Bloomfield, NJ, USA.ORCID 0000-0002-4687-7612
Ranjith RamasamyDepartment of Urology, Miller School of Medicine, University of Miami, Miami, FL, USA.ORCID 0000-0003-1387-7904
Liliana RamosDivision of Reproductive Medicine, Department of Obstetrics and Gynaecologie, Radboud UMC, Nijmegen, The Netherlands.ORCID 0000-0002-4269-013X
Nathalie RivesService Laboratoire de Biologie de la Reproduction-CECOS, Equipe Physiopathologie Surrénalienne et Gonadique, Unité Inserm 1239 NorDic, CHU-Hôpitaux de Rouen, UFR Santé-Université de Rouen, Rouen, France.ORCID 0000-0001-9102-1111
Eduardo Rs RoldanDepartment of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales (CSIC), Madrid, Spain.ORCID 0000-0002-7545-4248
Susan RothmannFertility Solutions Inc., Warrensville Heights, OH, USA.ORCID 0000-0002-9738-0913
Denny SakkasBoston IVF, Boston, MA, USA.ORCID 0000-0002-9509-6791
Andrea SaloniaUniversity Vita-Salute San Raffaele, Milan, Italy.ORCID 0000-0002-0595-7165
Maria Cristina Sánchez-PozoDepartment of Clinical Chemistry and Molecular Biology, Virgen del Rocío University Hospital, Seville, Spain.ORCID 0000-0002-4908-8758
Rosanna SapiroDepto de Histologia y Embriología, Facultad de Medicina, Gral. Flores, Uruguay.ORCID 0000-0002-9755-9016
Stefan SchlattCentre of Reproductive Medicine and Andrology, Münster, Germany.ORCID 0000-0002-7571-5313
Peter N SchlegelDepartment of Urology, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-7129-8137
Hans-Christian SchuppeSection of Andrology, Department of Urology, Pediatric Urology & Andrology, Justus-Liebig-University/University Hospital of Giessen-Marburg, Giessen, Germany.ORCID 0000-0002-0874-0439
Rupin ShahLilavati Hospital & Research Centre, Mumbai, India.ORCID 0000-0002-7868-5949
Niels E SkakkebækDepartment of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-4282-8020
Katja TeerdsHuman and Animal Physiology, Wageningen University, Wageningen, The Netherlands.ORCID 0000-0002-0930-1198
Igor ToskinWHO Department of Sexual and Reproductive Health and Research (includes the UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction-HRP), Geneva, Switzerland.ORCID 0000-0003-3046-7368
Herman TournayeCentre for Reproductive Medicine, Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0002-9863-9309
Paul J TurekThe Turek Clinic, San Francisco, CA, USA.ORCID 0000-0002-3034-5320
Gerhard van der HorstMedical Bioscience, University of the Western Cape, Bellville, South Africa.ORCID 0000-0003-2194-6818
Monica Vazquez-LevinIBYME, CONICET-FIBYME, Buenos Aires, Argentina.ORCID 0000-0002-4463-6532
Christina WangClinical and Translational Science Institute, The Lundquist Institute, Torrance, CA, USA.ORCID 0000-0002-8231-792X
Alex WetzelsFertility Laboratory, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0003-1758-0999
Theodosia ZeginiadouThessaloniki Andrology Laboratory-Hellenic Sperm Bank, Thessaloniki, Greece.ORCID 0000-0002-5241-9845
Armand ZiniDivision of Urology, Department of Surgery, St Mary's Hospital, McGill University, Montreal, Canada.ORCID 0000-0002-2194-5578
Funding
Role of BHC80 in spermatogenesisR03HD101650 · NICHD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HOFMANN, MARIE-CLAUDE CATHERINE · 2020 to 2021
$162kNICHD NIH HHS R03 HD101650World Health Organization 001
Abstract
Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concordant documents have been published: the 6th edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen, and the International Standard ISO 23162:2021. With these tools, we propose that authors should be instructed to follow these laboratory methods in order to publish studies in peer-reviewed journals, preferable by using a checklist as suggested in an Appendix to this article.
Indexed as
SemenSemen AnalysisHumansPeer ReviewPublishingReproducibility of Resultsandrologybasic semen examinationjournal requirementslaboratory trainingpatient securityquality controlreproducibilityreproductive medicinescience developmentstandardized laboratory procedures
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Read underepoch 390
Registered trials
NCT06188936ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.