Evidence map›Paper›PMID 36111637›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2022

Influence of rigid lens decentration and rotation on visual image quality in normal and keratoconic eyes.

Jos J Rozema, Gareth D Hastings, Marta Jiménez-García, Carina Koppen, Raymond A Applegate

Open access · greenAbstract read
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Impact of contact lens correction on wavefront aberrations and vision quality in keratoconus.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jos J RozemaVisual Optics Lab Antwerp (VOLANTIS), Faculty of Medicine and Health Sciences, Antwerp University, Wilrijk, Belgium.ORCID 0000-0001-8124-8646
Gareth D HastingsCollege of Optometry, University of Houston, Houston, Texas, USA.ORCID 0000-0001-8959-5984
Marta Jiménez-GarcíaVisual Optics Lab Antwerp (VOLANTIS), Faculty of Medicine and Health Sciences, Antwerp University, Wilrijk, Belgium.ORCID 0000-0002-2839-9696
Carina KoppenVisual Optics Lab Antwerp (VOLANTIS), Faculty of Medicine and Health Sciences, Antwerp University, Wilrijk, Belgium.ORCID 0000-0002-7728-7260
Raymond A ApplegateCollege of Optometry, University of Houston, Houston, Texas, USA.ORCID 0000-0002-4667-4364
University of Antwerp · BECenter for Innovation · USUniversity of Houston · US

Funding

Research Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI VALLABH E DAS · 1988 to 2026
$16.4M
Optical aberration and visual performance in highly aberrated eyesR01EY019105 · NEI · UNIVERSITY OF HOUSTON · PI APPLEGATE, RAYMOND A, MARSACK, JASON D · 2009 to 2018
$2.9M
ABERRATIONS OF EYES IN NORMAL CLINICAL POPULATIONR01EY008520 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI APPLEGATE, RAYMOND A · 1991 to 2010
$2.8M
NEI NIH HHS P30 EY007551NEI NIH HHS R01 EY008520NEI NIH HHS R01 EY019105
6 · The paper itself

Abstract

purposeTo investigate whether the movement of a rigid sphero-cylindrical contact lens has a greater impact on the visual image quality in highly aberrated eyes than in normal eyes.

methodsFor 20 normal and 20 keratoconic SyntEyes, a previously determined best sphero-cylindrical rigid lens was permitted to shift by up to ±1 mm from the line of sight and rotate up to ±15°. Each of the 52,111 lens locations sampled was ray-traced to determine the influence on the wavefront aberration. In turn, the logarithm of visual Strehl ratio (log

resultsThe variations in image quality within the misalignment space were unique to each eye. A two-letter loss was generally reached with smaller misalignments in keratoconic eyes (10.5 ± 4.7° of rotation or 0.27 ± 0.13 mm of shift) than in normal eyes (13.4 ± 1.8° and 0.39 ± 0.15 mm, respectively) due to larger cylindrical errors. For keratoconic eyes, on average, 14.4 ± 14.9% of misalignment space saw VSX values above the lower normal VSX threshold, well below the values of normal eyes of 48.5 ± 18.5%. In some eyes, a specific combination of lens shift and lens rotation away from the line of sight leads to a simulated improvement in visual image quality.

conclusionVariations in visual image quality due to the misalignment of rigid sphero-cylindrical contact lens corrections are larger for keratoconic eyes than for normal eyes. In some cases, a specific misalignment may improve visual image quality, which could be considered in the design of the next generation of rigid contact lenses.

Indexed as

Contact LensesKeratoconusEyeHumansRotationVisual Acuitycontact lens alignmentkeratoconusrefractive correctionstatistical eye model

Identifiers

PMID36111637
PMCPMC9547948
OpenAlexW4296033952

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.