Evidence map›Paper›PMID 36111619›Full record

ArticleBJPsych open2022

Life events and psychosis: case-control study from India, Nigeria, and Trinidad and Tobago.

Ibidunni O Oloniniyi, Helen A Weiss, Sujit John, Oluyomi Esan, Maia Hibben, Vikram Patel, Robin M Murray, Alex Cohen, Gerard Hutchinson, Oye Gureje and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJPsych open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 5 countries.

Ibidunni O OloniniyiDepartment of Health Services and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.ORCID https://orcid.org/0000-0002-2272-5155
Helen A WeissMRC International Statistics and Epidemiology Group, London School of Hygiene & Tropical Medicine, UK.
Sujit JohnDepartment of Psychiatry, Schizophrenia Research Foundation, India.
Oluyomi EsanDepartment of Psychiatry, University of Ibadan, Nigeria.
Maia HibbenDepartment of Psychiatry, Faculty of Medical Sciences, University of the West Indies, Trinidad and Tobago.
Vikram PatelDepartment of Global Health and Social Medicine, Harvard Medical School, Massachusetts, USA; and Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Harvard University, Massachusetts, USA.
Robin M MurrayDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Alex CohenCentre for Global Mental Health, London School of Hygiene & Tropical Medicine, UK.ORCID https://orcid.org/0000-0001-5040-0342
Gerard HutchinsonDepartment of Psychiatry, Faculty of Medical Sciences, University of the West Indies, Trinidad and Tobago.
Oye GurejeWHO Collaborating Centre for Research and Training in Mental Health, Neuroscience and Substance Abuse, Department of Psychiatry, University of Ibadan, Nigeria.
Rangaswamy TharaDepartment of Psychiatry, Schizophrenia Research Foundation, India.
Craig MorganESRC Centre for Society and Mental Health, King's College London, UK.ORCID https://orcid.org/0000-0002-1386-2369
Tessa RobertsESRC Centre for Society and Mental Health, King's College London, UK.ORCID https://orcid.org/0000-0001-8584-4162
King's College London · GBLondon School of Hygiene & Tropical Medicine · GBSchizophrenia Research Foundation · INUniversity of Ibadan · NGUniversity of the West Indies · TTHarvard University · US

Funding

Scaling up services for people with psychosis in Nigeria: a pilot studyR21MH093304 · NIMH · LONDON SCH/HYGIENE & TROPICAL MEDICINE · PI COHEN, ALEXANDER, GUREJE, OYEWUSI · 2011 to 2012
$220k
Medical Research Council MR/P025927/1Medical Research Council MR/R010161/1NIMH NIH HHS R21 MH093304Wellcome TrustWellcome Trust WT094525
6 · The paper itself

Abstract

backgroundThere is evidence of an association between life events and psychosis in Europe, North America and Australasia, but few studies have examined this association in the rest of the world.

aimsTo test the association between exposure to life events and psychosis in catchment areas in India, Nigeria, and Trinidad and Tobago.

methodWe conducted a population-based, matched case-control study of 194 participants in India, Nigeria, and Trinidad and Tobago. Cases were recruited through comprehensive population-based, case-finding strategies. The Harvard Trauma Questionnaire was used to measure life events. The Screening Schedule for Psychosis was used to screen for psychotic symptoms. The association between psychosis and having experienced life events (experienced or witnessed) was estimated by conditional logistic regression.

resultsThere was no overall evidence of an association between psychosis and having experienced or witnessed life events (adjusted odds ratio 1.19, 95% CI 0.62-2.28). We found evidence of effect modification by site (

conclusionsThis study found no overall evidence of an association between witnessing or experiencing life events and psychotic disorder across three culturally and economically diverse countries. There was preliminary evidence that the association varies between settings.

Indexed as

Indialife eventsNigeriaPsychosisTrinidad and Tobago

Identifiers

PMID36111619
PMCPMC9534879
OpenAlexW4296033274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.