Evidence map›Paper›PMID 36111572›Full record

ArticleJournal of Zhejiang University. Science. B

BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation.

Mengdan Yu, Qianwei Zhao, Jinxia Li, Fang Xu, Zhibiao Zhang, Yixian Liu, Liping Dai, Bingxia Zhang, Jianying Zhang, Jintao Zhang

Open access · greenAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mengdan YuHenan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
Qianwei ZhaoHenan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
Jinxia LiSchool of Basic Medical Sciences, Academy of Medical Science, Zhengzhou University, Zhengzhou 450052, China.
Fang XuHenan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
Zhibiao ZhangSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Yixian LiuHenan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
Liping DaiHenan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
Bingxia ZhangSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.
Jianying ZhangHenan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China. jtzhang@zzu.edu.cn, jianyingzhang@hotmail.com.
Jintao ZhangHenan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China. jtzhang@zzu.edu.cn.
Zhengzhou University · CN

Funding

the Key Scientific and Technological Project of Henan Province 212102310124 and 222102310083the Major Project of Science and Technology in Henan Province 161100311400the National Science and Technology Major Project of China 2018ZX10302205the Natural Science Foundation of Henan Province 182300410361 and 222300420306the Project of Basic Research Fund of Henan Institute of Medical and Pharmacological Sciences 2022BP0103
6 · The paper itself

Abstract

Lung cancer is one of the most prevalent and malignant cancers, among which lung adenocarcinoma (LUAD) accounts for the majority and remains a major cause of cancer-related mortality worldwide (Cui et al., 2019). Despite the growing intensity of research on the pathobiology and progression of lung cancer and the fact that many genes have been identified as potential drivers and targets for therapy (Luo et al., 2019; Zhang et al., 2019), the treatment and prognosis of lung cancer patients have hardly improved. Therefore, this study aimed to investigate the precise mechanism of lung cancer development and explore efficient diagnostic and therapeutic methods for clinical treatment.

Indexed as

Adenocarcinoma of LungLung NeoplasmsTransaminasesHumansMitochondriaNF-kappa BBCAT1 protein, humanNF-kappa BTransaminases

Identifiers

PMID36111572
PMCPMC9483610
OpenAlexW4296027045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.