ArticleESC heart failure2022
Incidence and impact of atrial fibrillation in heart failure patients: real-world data in a large community.
Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Incident Atrial Fibrillation and Flutter in Patients With Pulmonary Arterial Hypertension: Influence of Right Ventricular Dilatation and Reduced Right Atrial Function.Journal of the American Heart Association · 2026Observational
- AI-driven voltage map analysis for optimizing catheter ablation strategy in atrial fibrillation: a proof-of-concept study.European heart journal. Digital health · 2026Article
- Heart-rate-derived variability measures and in-hospital mortality in critically ill patients with heart failure and atrial fibrillation: insights from the MIMIC-IV database.BMC cardiovascular disorders · 2026Article
- Left ventricular and atrial strain and the risk of mortality and rehospitalization in heart failure.Echo research and practice · 2026Article
- Impact of atrial fibrillation status on clinical outcomes in patients admitted with heart failure.International journal of cardiology. Heart & vasculature · 2026Article
- Catheter Ablation as an Early Rhythm-control Strategy in Patients with Atrial Fibrillation and Heart Failure.Arrhythmia & electrophysiology review · 2026Review
- Predicting heart failure decompensation: focus on non-invasive monitoring.Cardiology journal · 2026Review
- Heart Failure in Lebanon: A Glimpse into the Reality of Growing Burden.Diagnostics (Basel, Switzerland) · 2025Article
- The controversies in the clinical management of β-blockers in acute heart failure induced by rapid atrial fibrillation: A narrative review.American heart journal plus : cardiology research and practice · 2025Review
- Improvement of Renal Function in Atrial Fibrillation Patients via Catheter Ablation and Left Atrial Appendage Closure: A Case Report.The American journal of case reports · 2025Article
- Edoxaban Safety and Effectiveness in Real-Life Patients with Heart Failure and Atrial Fibrillation: EMAYIC Study.Journal of clinical medicine · 2025Article
- SGLT2 Inhibitors and the Risk of Arrhythmias in Heart Failure: A Network Meta-Analysis.Journal of clinical medicine · 2025Review
- Resolution of oral anticoagulation-resistant left atrial appendage thrombus by cardiac resynchronization therapy and atrioventricular nodal ablation.Journal of cardiology cases · 2025Article
- The efficacy and safety of sodium-glucose cotransporter 2 inhibitors in patients aged over 80 years with heart failure.ESC heart failure · 2025Article
- Incidence and prognostic significance of atrial fibrillation in patients with tako-tsubo syndrome-systematic review and meta-analysis.Caspian journal of internal medicine · 2025Review
- Cryoablation and radiofrequency ablation during mitral valve surgery for rheumatic mitral valve disease: a retrospective cohort study.Frontiers in cardiovascular medicine · 2025Article
- Elevated plasma protein carbonylation increases the risk of ischemic cerebrovascular events in patients with atrial fibrillation: association with a prothrombotic state.Journal of thrombosis and thrombolysis · 2024Article
- Management of Left Atrial Tachyrhythms in the Setting of HFpEF with Pulsed-Field Ablation: Treating Fire with Water?Therapeutics · 2024Article
- Enhanced Levels of Adiposity, Stretch and Fibrosis Markers in Patients with Coexistent Heart Failure and Atrial Fibrillation.Journal of cardiovascular translational research · 2024Article
- The Optimal Management of Patients with Atrial Fibrillation and Acute Heart Failure in the Emergency Department.Medicina (Kaunas, Lithuania) · 2023Review
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe objective of the present study is to assess the bidirectional association between heart failure (HF) and atrial fibrillation (AF) using real-world data. METHODS AND
resultsFrom an electronic health recording with a population of 3 799 885 adult subjects, those with prevalent or incident HF were selected and followed throughout a study period of 5 years. Prevalence and incidence of AF, and their impact in the risk for acute HF hospitalization, worsening renal function, ischaemic and haemorrhagic stroke, and all-cause mortality were identified. We analysed all incident and prevalent patients with HF and AF, 128 086 patients (S1), and subsequently analysed a subset of patients with incident HF and AF, 57 354 patients (S2). We analysed all incident and prevalent patients with HF and AF, 128 086 patients (S1), and subsequently a subset of patients with incident HF and AF, 57 354 patients (S2). The prevalence of AF was 59 906 (46.7%) of the HF patients, while incidence in the S2 was 231/1000 patients/year. In both cohorts, S1 and S2, AF significantly increases the risk of acute heart failure hospitalization [incidence 79.1/1000 and 97.5/1000 patients/year; HR 1.53 (1.48-1.59 95% CI) and HR 1.32 (1.24-1.41 95% CI), respectively], risk of decreased renal function (eGFR reduced by >20%) [66.2/1000 and 94.0/1000 patients/year; HR 1.13 (1.09-1.18 95% CI) and HR 1.22 (1.14-1.31 95% CI), respectively] and all-cause mortality [203/1000 and 294/1000 patients/year; HR 1.62 (1.58-1.65 95% CI) and HR 1.65 (1.59-1.70 95% CI), respectively]. The number of episodes of hospitalization for acute heart failure was also significantly higher in the AF patients (27 623 vs. 10 036, P < 0.001). However, the risk for ischaemic stroke was reduced in the AF subjects [HR 0.66 (0.63-0.74 95% CI)], probably due to the anticoagulant treatment.
conclusionsAF is associated with an increment in the risk of episodes of acute heart failure as well as decline of renal function and increment of all-cause mortality.
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