Evidence map›Paper›PMID 36111332›Full record

ArticleFrontiers in cell and developmental biology2022

A heterozygous p.S143P mutation in

Gun West, Minttu Turunen, Anna Aalto, Laura Virtanen, Song-Ping Li, Tiina Heliö, Annika Meinander, Pekka Taimen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Epigenetics inCells · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gun WestInstitute of Biomedicine and FICAN West Cancer Centre, University of Turku, Turku, Finland.
Minttu TurunenInstitute of Biomedicine and FICAN West Cancer Centre, University of Turku, Turku, Finland.
Anna AaltoInFLAMES Research Flagship Center, University of Turku and Åbo Akademi University, Turku, Finland.
Laura VirtanenInstitute of Biomedicine and FICAN West Cancer Centre, University of Turku, Turku, Finland.
Song-Ping LiInstitute of Biomedicine and FICAN West Cancer Centre, University of Turku, Turku, Finland.
Tiina HeliöHeart and Lung Center Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Annika MeinanderInFLAMES Research Flagship Center, University of Turku and Åbo Akademi University, Turku, Finland.
Pekka TaimenInstitute of Biomedicine and FICAN West Cancer Centre, University of Turku, Turku, Finland.
University of Turku · FIÅbo Akademi University · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lamins A and C are nuclear intermediate filament proteins that form a proteinaceous meshwork called lamina beneath the inner nuclear membrane. Mutations in the

Indexed as

autophagydegradationdisease mutationslamin A/C (LMNA)ubiquitin-proteasome degradation systemubiquitin (Ub)

Identifiers

PMID36111332
PMCPMC9468711
OpenAlexW4293546623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.