Evidence map›Paper›PMID 36111305›Full record

SynthesisFrontiers in psychiatry2022

Assessment of the relationship between living alone and the risk of depression based on longitudinal studies: A systematic review and meta-analysis.

Daolin Wu, Fuwei Liu, Shan Huang

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  9. Social cohesion, social capital and mental health: current evidence and future research directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  10. Observational
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  12. The Role of Family Interaction Frequency on Depressive Symptoms in Korean Older Adults Aged ≥80 and Living Alone.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026
    Article
  13. Health-related quality of life of single-person households in the United States: results from the 2014-2023 Behavioral Risk Factor Surveillance System.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daolin WuDepartment of Sleep Medicine, Ganzhou People's Hospital, Ganzhou, China.
Fuwei LiuDepartment of Cardiology, Ganzhou People's Hospital, Ganzhou, China.
Shan HuangDepartment of Psychiatry, The Third People's Hospital of Ganzhou, Ganzhou, China.
Ganzhou People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Living alone is one of the most common psychosocial factors that may have an impact on lifestyle management and health status. Although many previous cross-sectional studies have found that living alone increases the risk of depression. However, this risk has rarely been assessed on the basis of longitudinal studies. Therefore, we will explore this relationship on the basis of longitudinal studies. Methods: We systematically searched Pubmed, Embase, and Cochrane databases up to May 2022. Adjusted odds ratios (ORs), and 95% confidence intervals (CIs) were pooled by a random-effects model using an inverse variance method. Results: Seven studies (six cohort studies and one case-control study) were included in our study. A total of 123,859 without a history of psychosis individuals were included, and the proportion of females was 65.3%. We applied a random-effects model to minimize the heterogeneity. Overall, the pooled data suggest that people living alone are associated with an increased risk of depression compared to those who do not live alone (OR 1.42, 95%CI 1.19-1.70). Conclusion: Compared to people who live with others, living alone increases the risk of depression. Only cross-sectional studies and a few longitudinal studies currently support this association; more high-quality studies will be required in the future to confirm this causal association.

Indexed as

depressionliving alonelongitudinal studiesmeta-analysissystematic review

Identifiers

PMID36111305
PMCPMC9468273
OpenAlexW4293770169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.