Evidence map›Paper›PMID 36111220›Full record

ArticleNeuropsychiatric disease and treatment2022

Serum Uric Acid to Serum Creatinine Ratio and Risk of Stroke Recurrence in Young Adults with Ischemic Stroke.

Xiaohong Sun, Jie Lv, Zhenghuan Wu, Jun Shi, Hongwei Huang

Abstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Repeated Health Screening Measures and Incident Ischemic Stroke: Evidence From a Korean Population Study.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaohong SunDepartment of Neurology, People's Hospital of Liyang, Changzhou, Jiangsu, 213300, People's Republic of China.
Jie LvDepartment of Neurology, People's Hospital of Liyang, Changzhou, Jiangsu, 213300, People's Republic of China.
Zhenghuan WuDepartment of Neurology, People's Hospital of Liyang, Changzhou, Jiangsu, 213300, People's Republic of China.
Jun ShiDepartment of Neurology, People's Hospital of Liyang, Changzhou, Jiangsu, 213300, People's Republic of China.
Hongwei HuangDepartment of Neurology, People's Hospital of Liyang, Changzhou, Jiangsu, 213300, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Serum uric acid to serum creatinine ratio (SUA/SCr) is associated with metabolic and cardiovascular diseases. We aimed to investigate the association between SUA/SCr and stroke recurrence among young adults with ischemic stroke. Methods: A total of 428 young patients with ischemic stroke were included in the present study. SUA/SCr was calculated from the concentration of serum uric acid and creatine (uric acid/creatine). Cox proportional regression models were performed to evaluate the association between SUA/SCr and stroke recurrence. Kaplan-Meier curves were used to compare recurrence rates in different quantiles of SUA/SCr. Results: During a median follow-up of 3.14 years, 51 (10.7%) patients had stroke recurrence. Multivariable analyses indicated that SUA/SCr was associated with stroke recurrence after being adjusted for potential confounders (quantile four versus quantile one: hazard ratio: 3.420; 95% confidence interval: 1.426-8.200; Conclusion: SUA/SCr was positively associated with the risk of stroke recurrence among young adults with ischemic stroke. Further prospective studies are warranted to assess the causality between SUA/SCr and the development of stroke recurrence among young adults.

Indexed as

ischemic strokerecurrenceuric acidyoung adults

Identifiers

PMID36111220
PMCPMC9469936

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.