Evidence map›Paper›PMID 36111103›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2022

Alcohol's effects during uncertain and uncontrollable stressors in the laboratory.

Daniel E Bradford, Jack M Shireman, Sarah J Sant'Ana, Gaylen E Fronk, Susan E Schneck, John J Curtin

Abstract read
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Increasing ecological validity in neuropsychopharmacology research on the relationship between alcohol use and uncertain stressors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  4. A social contextual review of the effects of alcohol on emotion.Pharmacology, biochemistry, and behavior · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel E BradfordDepartment of Psychology, University of Miami, Coral Gables, Florida, USA.
Jack M ShiremanNeuroscience Training Program, University of Wisconsin, Madison, Wisconsin, USA.
Sarah J Sant'AnaDepartment of Psychology, University of Wisconsin, Madison, Wisconsin, USA.
Gaylen E FronkDepartment of Psychology, University of Wisconsin, Madison, Wisconsin, USA.
Susan E SchneckDepartment of Psychology, University of Wisconsin, Madison, Wisconsin, USA.
John J CurtinDepartment of Psychology, University of Wisconsin, Madison, Wisconsin, USA.

Funding

RCT targeting noradrenergic stress mechanisms in alcoholism with doxazosinR01AA024388 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI CURTIN, JOHN J. · 2015 to 2019
$2.1M
Dynamic, real-time prediction of alcohol use lapse using mHealth technologiesR01AA024391 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI CURTIN, JOHN J. · 2015 to 2019
$1.9M
NIAAA NIH HHS R01 AA024388NIAAA NIH HHS R01 AA024391
6 · The paper itself

Abstract

Alcohol's effects on reactivity to stressors depends on the nature of the stressor and the reactivity being assessed. Research identifying characteristics of stressors that modulate reactivity and clarifies the neurobehavioral, cognitive, and affective components of this reactivity may help prevent, reduce or treat the negative impacts of acute and chronic alcohol use with implications for other psychopathology involving maladaptive reactivity to stressors. We used a novel, multi-measure, cued electric shock stressor paradigm in a greater university community sample of adult recreational drinkers to test how alcohol (N=64), compared to No-alcohol (N=64), effects reactivity to stressors that vary in both their perceived certainty and controllability. Preregistered analyses suggested alcohol significantly dampened subjective anxiety (self-report) and defensive reactivity (startle potentiation) more during uncertain than during certain stressors regardless of controllability, suggesting that stressor uncertainty -but not uncontrollability- may be sufficient to enhance alcohol's stress reactivity dampening and thus negative reinforcement potential.

Identifiers

PMID36111103
PMCPMC9472562

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.