Evidence map›Paper›PMID 36111088›Full record

ArticleIndian journal of anaesthesia2022

Reliability of analgesia nociception index (ANI) and surgical pleth index (SPI) during episodes of bleeding - A pilot study.

Sindhupriya Muthukalai, Sonia Bansal, Dhritiman Chakrabarti, Gs Umamaheswara Rao

Abstract read
In one paragraph

Article in Indian journal of anaesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sindhupriya MuthukalaiDepartment of Neuroanaesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Sonia BansalDepartment of Neuroanaesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Dhritiman ChakrabartiDepartment of Neuroanaesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Gs Umamaheswara RaoDepartment of Neuroanaesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Analgesia Nociception Index (ANI) and Surgical Pleth Index (SPI) are measures of nociception-antinociception balance during general anaesthesia. The validity of these two monitors during autonomic changes brought about by intraoperative blood loss and noradrenaline infusion has not been studied earlier. The primary objective of the study was to determine the effect of bleeding on ANI and SPI. The secondary objective was to observe the effect of noradrenaline infusion on ANI and SPI and the correlation between ANI and SPI. Methods: In this prospective observational study, 43 patients undergoing surgery for excision of a meningioma or for traumatic brain injury were included. Heart rate, mean arterial pressure, ANI, SPI, response and state entropy were recorded every 5 min from anaesthetic induction till skin closure. ANI and SPI values before bleeding were compared with the values following bleeding. The effect of bleeding and noradrenaline on ANI and SPI were studied using linear mixed effect model. Results: Bleeding increased the values of ANI and the increase was higher in the presence of noradrenaline and it was statistically significant (P = 0.028 and 0.023). SPI was not affected by bleeding or with noradrenaline infusion. ANI and SPI had a poor negative correlation (r = - 0.01). Conclusion: Values of ANI increased significantly during episodes of intraoperative acute blood loss and with co-administration of noradrenaline. SPI seems to be more dependable when compared to ANI under such conditions.

Indexed as

Analgesia nociceptionblood lossneurosurgical proceduresnorepinephrinepain measurementplethysmographysurgical

Identifiers

PMID36111088
PMCPMC9469000

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.