Evidence map›Paper›PMID 36110894›Full record

ArticleGeburtshilfe und Frauenheilkunde2022

Update Breast Cancer 2022 Part 3 - Early-Stage Breast Cancer.

Tanja N Fehm, Manfred Welslau, Volkmar Müller, Diana Lüftner, Florian Schütz, Peter A Fasching, Wolfgang Janni, Christoph Thomssen, Isabell Witzel, Erik Belleville and 14 more

Open access · hybridAbstract read
In one paragraph

Article in Geburtshilfe und Frauenheilkunde, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 1 country.

Tanja N FehmDepartment of Gynecology and Obstetrics, University Hospital Düsseldorf, Düsseldorf, Germany.
Manfred WelslauOnkologie Aschaffenburg, Aschaffenburg, Germany.
Volkmar MüllerDepartment of Gynecology, Hamburg-Eppendorf University Medical Center, Hamburg, Germany.
Diana LüftnerImmanuel Hospital Märkische Schweiz & Medical University of Brandenburg Theodor-Fontane, Brandenburg, Buckow, Germany.
Florian SchützGynäkologie und Geburtshilfe, Diakonissen-Stiftungs-Krankenhaus Speyer, Speyer, Germany.
Peter A FaschingErlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Wolfgang JanniDepartment of Gynecology and Obstetrics, Ulm University Hospital, Ulm, Germany.
Christoph ThomssenDepartment of Gynaecology, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Isabell WitzelDepartment of Gynecology, Hamburg-Eppendorf University Medical Center, Hamburg, Germany.
Erik BellevilleClinSol GmbH & Co KG, Würzburg, Germany.
Michael UntchClinic for Gynecology and Obstetrics, Breast Cancer Center, Gynecologic Oncology Center, Helios Klinikum Berlin Buch, Berlin, Germany.
Marc ThillAgaplesion Markus Krankenhaus, Department of Gynecology and Gynecological Oncology, Frankfurt am Main, Germany.
Hans TeschOncology Practice at Bethanien Hospital, Frankfurt am Main, Germany.
Nina DitschDepartment of Gynecology and Obstetrics, University Hospital Augsburg, Augsburg, Germany.
Michael P LuxKlinik für Gynäkologie und Geburtshilfe, Frauenklinik St. Louise, Paderborn, St. Josefs-Krankenhaus, Salzkotten, St. Vincenz Krankenhaus GmbH, Germany.
Bahriye AktasDepartment of Gynecology, University of Leipzig Medical Center, Leipzig, Germany.
Maggie Banys-PaluchowskiDepartment of Gynecology and Obstetrics, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
Andreas SchneeweissNational Center for Tumor Diseases (NCT), Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany.
Cornelia Kolberg-LiedtkeDepartment of Gynecology and Obstetrics, University Hospital Essen, Essen, Germany.
Andreas D HartkopfDepartment of Gynecology and Obstetrics, Ulm University Hospital, Ulm, Germany.
Achim WöckelDepartment of Gynecology and Obstetrics, University Hospital Würzburg, Würzburg, Germany.
Hans-Christian KolbergDepartment of Gynecology and Obstetrics, Marienhospital Bottrop, Bottrop, Germany.
Nadia HarbeckBreast Center, Department of Gynecology and Obstetrics and CCC Munich LMU, LMU University Hospital, Munich, Germany.
Elmar StickelerDepartment of Gynecology and Obstetrics, RWTH University Hospital Aachen, Aachen, Germany.
University Hospital Ulm · DEAgaplesion Markus Hospital · DECardiovascular Center Bethanien · DEComprehensive Cancer Center Erlangen · DEDiakonissenkrankenhaus · DEEssen University Hospital · DEHeinrich Heine University Düsseldorf · DEHelios Hospital Berlin-Buch · DEKlinikum Aschaffenburg · DELeipzig University · DELudwig-Maximilians-Universität München · DEMarienhospital Bottrop · DEMartin Luther University Halle-Wittenberg · DENational Center for Tumor Diseases · DESt. Josef Krankenhaus · DEUniversität Hamburg · DEUniversitätsklinikum Aachen · DEUniversitätsklinikum Würzburg · DEUniversity Hospital Augsburg · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review summarizes recent developments in the prevention and treatment of patients with early-stage breast cancer. The individual disease risk for different molecular subtypes was investigated in a large epidemiological study. With regard to treatment, new data are available from long-term follow-up of the Aphinity study, as well as new data on neoadjuvant therapy with atezolizumab in HER2-positive patients. Biomarkers, such as residual cancer burden, were investigated in the context of pembrolizumab therapy. A Genomic Grade Index study in elderly patients is one of a group of studies investigating the use of modern multigene tests to identify patients with an excellent prognosis in whom chemotherapy may be avoided. These and other aspects of the latest developments in the diagnosis and treatment of breast cancer are described in this review.

Indexed as

adjuvant treatmentbreast cancerchemotherapyearly stageendocrine therapyneoadjuvant treatment

Identifiers

PMID36110894
PMCPMC9470293
OpenAlexW4295838490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.