Evidence map›Paper›PMID 36110742›Full record

ArticleJournal of pharmacy & bioallied sciences2022

PCR-based Evaluation of Human Papillomavirus Genotypes in Oral Lichen Planus.

Aswathy K Vijayan, Arvind Muthukrishnan, Aparna M Nair, Shabna Fathima, Pratheeksha V Nair, John Roshan

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aswathy K VijayanDepartment of Oral Medicine and Radiology, PMS College of Dental Science and Research, Thiruvananthapuram, Kerala, India.
Arvind MuthukrishnanDepartment of Oral Medicine and Radiology, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.
Aparna M NairDepartment of Periodontics, PMS College of Dental Science and Research, Thiruvananthapuram, Kerala, India.
Shabna FathimaDepartment of Oral Medicine and Radiology, PMS College of Dental Science and Research, Thiruvananthapuram, Kerala, India.
Pratheeksha V NairDepartment of Prosthodontics, PMS College of Dental Science and Research, Thiruvananthapuram, Kerala, India.
John RoshanDepartment of Periodontics, PMS College of Dental Science and Research, Thiruvananthapuram, Kerala, India.
Noorul Islam College of Dental Science · INSaveetha University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of the study was to use polymerase chain reaction (PCR) to examine and compare the genotype distribution of human papillomavirus (HPV) in oral lichen planus (OLP). Materials and Methods: Deoxyribonucleic acid (DNA) was extracted from 20 OLP biopsy specimens. Conventional PCR assay employing consensus HPV primers was used to identify HPV DNA. Positive PCR samples were then subjected to PCR assay with HPV type-specific primers. Results: Out of the total 20 OLP specimens evaluated, eight samples (40%) were positive for HPV. Females had a 41.7% higher HPV-positive rate than males. The most common type in the HPV type-specific PCR assay was HPV-18 (75%), which is a high-risk type of HPV linked to malignant diseases. The erosive kind of OLP had the greatest percentage of HPV positives (50%). Conclusion: The present study confirms the detection of HPV in OLP lesions, as determined by PCR-coupled HPV gene sequencing, as well as its likely mechanism of malignant transformation.

Indexed as

Human Papillomavirus 16human papillomavirus 18lichen planusPCRpremalignant

Identifiers

PMID36110742
PMCPMC9469342
OpenAlexW4285218430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.