Evidence map›Paper›PMID 36110657›Full record

ArticleJournal of pharmacy & bioallied sciences2022

Detection of Human PapillomaVirus and its Association with Potentially Malignant Disorders and Oral Squamous Cell Carcinoma: A Retrospective Study.

Anushree Rathore, Anushree Tiwari, Maira Nazim, Anup Kumar Gupta, Mounica Gande, Jyothi Krishnakumar

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06721806 (Role of Platelet Rich Plasma in Bone Regeneration After Enucleation of Odontogenic Jaw Cysts), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06721806 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Role of Platelet Rich Plasma in Bone Regeneration After Enucleation of Odontogenic Jaw Cysts

TypeinterventionalSponsorAssiut UniversityRan2024 to 2027Enrolled42ConditionsPRP & Jaw CystsArmsPRP & bone regeneration
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 20 citations in OpenAlex.

  1. AnJournal of pharmacy & bioallied sciences · 2025
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  4. Journal of pharmacy & bioallied sciences · 2025
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  6. Journal of pharmacy & bioallied sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Anushree RathoreDepartment of Oral Pathology and Microbiology, Bhabha College of Dental Sciences, Madhya Pradesh, India.
Anushree TiwariResearch Analyst, American Academy of Orthopedic Surgeons, Chicago, IL, US.
Maira NazimDental Surgeon/House Officer, Private Practitioner, Fauji Foundation Hospital, Rawalpindi, Pakistan.
Anup Kumar GuptaCommunity Health Administration, The National Institute of Health and Family Welfare (NIHFW), New Delhi, India.
Mounica GandeHealthcare IT Consultant, Texas, US.
Jyothi KrishnakumarDentist, Private Practitioner, Austin, Texas, US.
American Academy of Orthopaedic Surgeons · USBhabha Hospital · INFoundation University Medical College · PKMethodist Healthcare · USNational Institute of Health and Family Welfare · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This study was carried out with the objective of recognizing the involvement of human papillomavirus (HPV) in conditions of oral squamous cell carcinoma (OSCC) and oral potentially malignant conditions and lesions. Materials and Methods: OSCC samples from thirty patients were collected and thirty paraffin-embedded, oral premalignant specimens were collected. It was decided to use as a negative control samples gingiva from healthy individuals who had no prior history of oral proliferative leukoplakia or OSCC. The samples were then processed using a paraffin-embedded tissue block method. Deoxyribonucleic acid will be extracted from the paraffin-embedded tumor sample of sixty case subjects and tested for the presence of HPV DNA using polymerase chain reaction. Results: In study Group 1, 24 samples were taken from males and 6 from females. In study Group 2, 26 cases were males and 4 were females. In Group 1, 16 cases of moderately differentiated and 14 cases of well differentiated each were present. No case of poorly differentiated were found. There was statistically no significant difference present between male and female when Group 1 and Group 2 was considered. In study Group 1, 0 samples had positive HPV DNA detection, whereas 30 samples had negative HPV DNA detection. In study Group 2, 0 samples had positive HPV DNA detection, whereas 30 samples had negative HPV expression. Conclusion: According to our findings, certain incidences of OSCC may be linked to HPV, however, this was not the case for all of the cancers.

Indexed as

Human papillomavirusoral squamous cell carcinomapotential malignant lesions

Identifiers

PMID36110657
PMCPMC9469399
OpenAlexW4285143155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.