Evidence map›Paper›PMID 36110530›Full record

ArticleFrontiers in pharmacology2022

Inflammation aggravated the hepatotoxicity of triptolide by oxidative stress, lipid metabolism disorder, autophagy, and apoptosis in zebrafish.

Chenqinyao Li, Changqing Zhang, Chengyue Zhu, Jie Zhang, Qing Xia, Kechun Liu, Yun Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chenqinyao LiBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Changqing ZhangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Chengyue ZhuBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Jie ZhangState Key Laboratory of Biobased Material and Green Papermaking, School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Qing XiaBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Kechun LiuBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Yun ZhangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Qilu University of Technology · CNShandong Academy of Sciences · CNNational Health and Family Planning Commission · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triptolide is a major compound isolated from the

Indexed as

hepatotoxicityinflammationlipid metabolismtriptolidezebrafish

Identifiers

PMID36110530
PMCPMC9468416
OpenAlexW4293536246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.