Evidence map›Paper›PMID 36110492›Full record

ReviewCureus2022

Does Vaccination Increase the Risk of Autism Spectrum Disorder?

Shaza A Mohammed, Shriya Rajashekar, Suganya Giri Ravindran, Meghana Kakarla, Musa Ausaja Gambo, Mustafa Yousri Salama, Nathalie Haidar Ismail, Pardis Tavalla, Pulkita Uppal, Pousette Hamid

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shaza A MohammedInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Shriya RajashekarInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Suganya Giri RavindranInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Meghana KakarlaInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Musa Ausaja GamboPediatrics and Child Health, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Mustafa Yousri SalamaInternal Medicine/Family Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Nathalie Haidar IsmailResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Pardis TavallaInternal Medicine/Family Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Pulkita UppalMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Pousette HamidNeurology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a developmental disorder that can cause significant social, communicative, and behavioral difficulties. With autism rates rising dramatically in recent years, researchers and concerned parents have theorized the causes of autism, and the subject has received much attention. Is the high rate of autism now due to increased diagnosis and reporting, changing autism definitions, or a rise in the number of people with ASD? People started to blame vaccines as a cause of the increased number of people with ASD. Vaccines and their connection to autism have been the subject of continuous debate. Some parents are concerned that vaccines, particularly the measles-mumps-rubella (MMR) vaccine and preservatives used in other childhood vaccines, may play a role in developing autism in their children. This systemic review explores the link between vaccination and autism in children. We conducted a literature search using PubMed and Google Scholar. We included papers written in the English language from 1998 to 2022, conducting human research that examines the relationship between vaccination and the development of autism using appropriate quality assessment tools. Two reviewers independently reviewed the content of the included studies. In total, 21 studies were deemed eligible.

Indexed as

autismautism spectrum disorderimmunizationmeasles mumps rubella (mmr)vaccination

Identifiers

PMID36110492
PMCPMC9464417
OpenAlexW4291635189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.