Evidence map›Paper›PMID 36110252›Full record

ArticlePathology oncology research : POR2022

O-Glycosylating Enzyme GALNT2 Predicts Worse Prognosis in Cervical Cancer.

Lixia Zhou, Huiqin Wu, Xingli Bai, Shuyun Min, Jiawen Zhang, Cunli Li

Open access · goldAbstract read
In one paragraph

Article in Pathology oncology research : POR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lixia ZhouDepartment of Obstetrics and Gynecology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huiqin WuDepartment of Obstetrics and Gynecology, Shanghai Songjiang District Maternal and Child Health Hospital, Shanghai, China.
Xingli BaiDepartment of Obstetrics and Gynecology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shuyun MinDepartment of Obstetrics and Gynecology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jiawen ZhangDepartment of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Cunli LiDepartment of Obstetrics and Gynecology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identification of novel biomarkers is helpful for the diagnosis and treatment of cervical cancer. Mucin glycosylating enzyme GALNT2 modulates mucin O-glycosylation, and has been revealed as a regulator of tumorigenesis in various cancers. However, the expression pattern of GALNT2 in cervical cancer is still unclear. In this study, we demonstrated that the mRNA expression and protein level of GALNT2 were increased in cervical high-grade intraepithelial neoplasia and tumor tissues compared with normal cervix tissues. Kaplan-Meier plotter showed that overexpression of GALNT2 was associated with worse overall survival in TCGA cohort (

Indexed as

Uterine Cervical NeoplasmsB7 AntigensCD47 AntigenFemaleHumansInterleukin-11MucinsN-AcetylgalactosaminyltransferasesPolypeptide N-acetylgalactosaminyltransferasePrognosisRNA, MessengerB7 AntigensCD276 protein, humanCD47 AntigenInterleukin-11MucinsN-AcetylgalactosaminyltransferasesPolypeptide N-acetylgalactosaminyltransferaseRNA, Messengeranti-tumor immune responsecervical cancerGALNT2immune-related biomarkersurvival

Identifiers

PMID36110252
PMCPMC9469784
OpenAlexW4293572727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.