Levels and health risk assessment of trace metals in honey from different districts of Bench Sheko Zone, Southwest Ethiopia.

This study aimed to determine the levels and potential health risks posed by trace metals (Zn, Cu, Mn, Cd, Cr, and Pb) obtained in honey samples. The honey samples were from Sheko, Guraferda, Mizan Aman Town, Debub Bench, and Semien Bench in Bench Sheko Zone, Southern Ethiopia, and levels of trace metals were determined using atomic absorption spectroscopy (AAS). The levels of trace metals in honey samples across the provinces ranged as follows; Zn (1.78-4.02 mg/kg), Cu(1.85-2.35 mg/kg), Mn (0.75-1.25 mg/kg), Cd (0.011-0.038 mg/kg), Cr (0.25-0.55 mg/kg), respectively. The level of Pb was not detected in all honey samples. The levels of trace metals obtained were lower than the maximum permissible limit set by WHO/FAO. Limit of detection (LOD) and quantification (LOQ) were ranged from 0.00045 to 0.005 and 0.0015 to 0.016, for the tested metals, respectively. The estimated recoveries of the method were ranged from 92.66% to 103.00% showed a good agreement of accuracy. The EDI values (mg/kg) of the investigated trace metals in all honey samples were less than the maximum tolerable daily intake (MTDI). The values of the target hazard quotient (THQ) and the hazard index (HI) were less than unity. The target cancer risk (TCR) values of Cd in all honey samples showed the lowest carcinogenic risks with values ranged from 3.34E-07 to 1.27E-06. However, the TCR value of Cr in all honey samples ranged from 1.03E-05 to 2.43E-05 and was in the moderate range. The