Evidence map›Paper›PMID 36110182›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Effects of Oral Administration of

Su-Young Kim, Jung Ok Lee, Yu-Jin Kim, You Na Jang, Jung Min Lee, A Yeon Park, Kwang-Ho Yoo, Beom Joon Kim

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Su-Young KimDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID https://orcid.org/0000-0002-3251-5813
Jung Ok LeeDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID https://orcid.org/0000-0002-0048-5322
Yu-Jin KimDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID https://orcid.org/0000-0002-1247-2887
You Na JangDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID https://orcid.org/0000-0002-0014-9783
Jung Min LeeDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID https://orcid.org/0000-0002-4670-2521
A Yeon ParkDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID https://orcid.org/0000-0002-4667-8875
Kwang-Ho YooDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID https://orcid.org/0000-0002-0137-6849
Beom Joon KimDepartment of Dermatology, College of Medicine, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID https://orcid.org/0000-0003-2320-7621
Chung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Probiotics are known to improve atopic dermatitis (AD) by inhibiting T helper 2 (Th2)-related reactions, restoring the Th2/T helper1 (Th1) cytokine ratio. The most popular probiotic is Materials and Methods: The effectiveness of oral GTB1 administration in improving AD was evaluated by visual evaluation, comparison of the lymph node sizes and spleen weights, histological evaluation, RT-qPCR, ELISA, and IHC analysis in the mouse model. Results: GTB1 improved AD symptoms, reduced epidermal thickness and mast cell numbers, decreased lymph node size and the spleen weight, increased filaggrin and loricrin protein levels, downregulated Th2 expression, and upregulated Th1 expression in a colony-forming unit-dependent manner. Conclusion: Oral administration of GTB1 isolated from green tea (

Identifiers

PMID36110182
PMCPMC9470305
OpenAlexW4294949099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.