Evidence map›Paper›PMID 36110153›Full record

ReviewCytotechnology2022

Status in molluscan cell line development in last one decade (2010-2020): impediments and way forward.

Soumya Balakrishnan, I S Bright Singh, Jayesh Puthumana

Abstract readReview
In one paragraph

Review in Cytotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Coating materials enhance urochordate primary cell culture adherence.In vitro cellular & developmental biology. Animal · 2026
    Article
  4. AdvancingBiology · 2026
    Article
  5. Article
  6. Advancing marine invertebrate cell line research: four key knowledge gaps.In vitro cellular & developmental biology. Animal · 2025
    Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Soumya BalakrishnanNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin, Kerala 682016 India.ORCID 0000-0001-9743-1162
I S Bright SinghNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin, Kerala 682016 India.ORCID 0000-0003-4482-2084
Jayesh PuthumanaNational Centre for Aquatic Animal Health, Cochin University of Science and Technology, Cochin, Kerala 682016 India.ORCID 0000-0002-3423-6420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the attempts that have started since the 1960s, not even a single cell line of marine molluscs is available. Considering the vast contribution of marine bivalve aquaculture to the world economy, the prevailing viral threats, and the dismaying lack of advancements in molluscan virology, the requirement of a marine molluscan cell line is indispensable. This synthetic review discusses the obstacles in developing a marine molluscan cell line concerning the choice of species, the selection of tissue and decontamination, and cell culture media, with emphasis given on the current decade 2010-2020. Detailed accounts on the experiments on the virus cultivation in vitro and molluscan cell immortalization, with a brief note on the history and applications of the molluscan cell culture, are elucidated to give a holistic picture of the current status and future trends in molluscan cell line development. Supplementary Information: The online version contains supplementary material available at 10.1007/s10616-022-00539-x.

Indexed as

Cell lineCulture mediumDecontaminationImmortalizationMolluscan cell cultureTransfectionTransformationVirus

Identifiers

PMID36110153
PMCPMC9374870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.