ArticleInternational journal of endocrinology2022
Association between Serum Cotinine Levels and Bone Mineral Density: An Analysis of the National Health and Nutrition Examination Survey (NHANES).
Article in International journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Mediating role of inflammatory markers in the relationship between cotinine levels and total bone mineral density.PloS one · 2025Article
- Associations between smoke exposure and osteoporosis or osteopenia in a US NHANES population of elderly individuals.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
Purpose: To investigate the relationship between serum cotinine and lumbar bone mineral density (BMD) among 7905 participants aged 30 years and over. Method: A total of 3945 men and 3960 women from the National Health and Nutrition Examination Survey 2011-2018 were included in this cross-sectional analysis. Independent variable was serum cotinine, which is a biomarker of cigarette exposure. The outcome variable was lumbar BMD. We investigated the associations of serum cotinine levels and lumbar BMD using multivariable linear regression models. Results: Serum cotinine concentration was negatively associated with lumbar BMD after adjustment of relevant covariables ( Conclusion: Our study suggested that elevated serum cotinine level correlated with decreased lumbar BMD, especially in women. This finding indicated that reducing cigarette exposure and maintaining serum cotinine at a low level may be beneficial to bone health for adults.
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