ArticleInternational journal of retina and vitreous2022
Acute retinal necrosis. Management and visual outcomes: a case series.
Article in International journal of retina and vitreous, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical Spectrum and Perspective in Bilateral Acute Retinal Necrosis: Systematic Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Predictors of retinal detachment and visual outcome in acute retinal necrosis: a 14-year retrospective cohort.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Outcomes of Patients with Acute Retinal Necrosis (ARN) presenting to a Canadian tertiary care centre: a 5-year retrospective cohort study.Journal of ophthalmic inflammation and infection · 2026Article
- Acute retinal necrosis presenting exudative retinal detachment: a case report.Frontiers in medicine · 2026Article
- A Systematic Approach to Managing Acute Visual Loss: A Comprehensive Review of Literature.Cureus · 2026Review
- Incidence and clinical characterization of retinal detachment in acute retinal necrosis: a global federated database analysis.Frontiers in ophthalmology · 2026Article
- Eye on cytomegalovirus: Unveiling the ophthalmic impact of cytomegalovirus.World journal of virology · 2025Article
- Analysis of prognostic factors in acute retinal necrosis using ultrawide-field fundus imaging.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Clinical characteristics and outcomes of acute retinal necrosis at different stages: a retrospective study.BMC ophthalmology · 2025Article
- Varicella Zoster Virus-Induced Retinitis and Retinal Detachment in an Immunocompetent Patient: A Case Report.The American journal of case reports · 2025Article
- Junctional proliferative vitreoretinopathy in rhegmatogenous retinal detachment secondary to viral retinitis in HIV.International ophthalmology · 2025Article
- Article
- Acute retinal necrosis in a patient with cervical malignant tumor treated with sintilimab: a case report and literature review.Frontiers in immunology · 2024Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study reports the functional and anatomical outcomes of eyes with acute retinal necrosis(ARN).
methodsThis is a retrospective case series conducted at a tertiary Eye Hospital from March 2015 to March 2020. Medical records of patients with clinical and laboratorial-Polymerase Chain Reaction (PCR)-diagnosis of ARN were reviewed. To identify factors related to the outcomes of visual acuity(VA) and retinal detachment (RD) over time, Cox proportional hazards regression modeling and survival analyses were used.
resultsTwenty-three eyes of 23 patients (16 male, 7 female) were reviewed. Based on the PCR results, 16 cases (69.6%) had Varicella zoster virus, 3 cases (13%) had Cytomegalovirus, 1 patient (4.3%) had Herpes simplex virus associated ARN, and 1 case (4.3%) had negative PCR. The incident rate for ≥ 2-line VA gain was 0.28/eye-year (EY) (95% CI 0.21 ± 0.26) while the rate of severe vision loss was 0.09/eye-year (95% CI 0.05 ± 0.08). The RD development was observed at a rate of 0.43/eye-year (0.42 ± 0.02), which occurred in 9 eyes with a mean time of 100 days after the initial presentation of ARN. Patients' age was the only factor associated with 2-line or more gain in VA over time with a hazard ratio of 0.921 (95% CI 0.854-0.993, P = 0.032).
conclusionsGenerally, although being crucial, treatment is not highly effective in improvement of VA and decrease of RD development, as well as vision loss, in patients with ARN. However, treatment prevents fellow eye involvement efficiently. Younger age is associated with better response to treatment and more chance to achieve better VA.
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