Evidence map›Paper›PMID 36109763›Full record

ArticleItalian journal of pediatrics2022

Non-syndromic bile duct paucity and non-IgE cow's milk allergy: a case report of challenging nutritional management and maltodextrin intolerance.

Irene Degrassi, Martina Chiara Pascuzzi, Enza D'Auria, Laura Fiori, Dario Dilillo, Gianluca Lista, Francesca Maria Castoldi, Francesco Cavigioli, Alessandra Bosetti, Alessandro Pellegrinelli and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Italian journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Irene DegrassiDepartment of Pediatrics, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy. irene.degrassi@asst-fbf-sacco.it.ORCID http://orcid.org/0000-0002-8123-7522
Martina Chiara PascuzziDepartment of Pediatrics, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Enza D'AuriaDepartment of Pediatrics, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Laura FioriDepartment of Pediatrics, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Dario DililloDepartment of Pediatrics, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Gianluca ListaDepartment of Pediatrics, Neonatal Intensive Care Unit, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Francesca Maria CastoldiDepartment of Pediatrics, Neonatal Intensive Care Unit, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Francesco CavigioliDepartment of Pediatrics, Neonatal Intensive Care Unit, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Alessandra BosettiDepartment of Pediatrics, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Alessandro PellegrinelliDepartment of Pathology, "L. Sacco" Hospital, Milan, 20157, Italy.
Gian Vincenzo ZuccottiDepartment of Pediatrics, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Elvira VerduciDepartment of Pediatrics, "Vittore Buzzi" Children's Hospital, Milan, 20154, Italy.
Ospedale dei Bambini Vittore Buzzi · ITUniversity of Milan · ITLuigi Sacco Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCholestasis in extremely premature infants (EPI) constitutes a nutritional challenge and maltodextrins have been reported as a possible strategy for hypoglycaemia. We aim to describe the nutritional management of an EPI with non-syndromic bile duct paucity (NSBDP) and feeding intolerance. CASE PRESENTATION: A patient, born at 27 weeks of gestational age, presented cholestatic jaundice at 20 days of life with a clinical picture of NSBDP. Patient's growth was insufficient with formula rich in medium-chain triglyceride (MCT) and branched-chain amino acids (BCAA). Due to frequent fasting hypoglicemic episodes, maltodextrins supplements were provided. He subsequently presented severe abdominal distension and painful crises, which required hospital admission and withdrawal of maltodextrins. Hypercaloric extensively hydrolysed formula provided weight gain, glycemic control, and parallel improvement in cholestasis.

conclusionsOur case suggests caution with the use of maltodextrins in infants, especially if premature. Commercial preparations for hepatopatic patients contain higher concentrations of MCTs and BCAAs, but personalized strategies must be tailored to each patient.

Indexed as

CholestasisMilk HypersensitivityAmino Acids, Branched-ChainAnimalsBile DuctsCattleFemaleHumansInfant, NewbornMalePolysaccharidesTriglyceridesAmino Acids, Branched-ChainmaltodextrinPolysaccharidesTriglyceridesBile duct paucityCholestasisHypoglycaemiaMaltodextrinPremature infants

Identifiers

PMID36109763
PMCPMC9479288
OpenAlexW4296026697

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.