ArticleNature communications2022
AC amplification gain in organic electrochemical transistors for impedance-based single cell sensors.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Organic Electrochemical Transistors for Real-Time Detection of Immune System Early Activation during Atezolizumab-Bevacizumab Treatment in Hepatocellular Carcinoma.ACS applied materials & interfaces · 2026Article
- A transistor-based point-of-care assay with lipid-capped sensory interface for clinical profiling of cardiovascular diseases.National science review · 2026Article
- Two-dimensional semiconductor-based active array for high-fidelity spatiotemporal monitoring of neural activities.Nature materials · 2026Article
- Organic Electrochemical Transistors for Neuromorphic Devices and Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Organic Electrochemical Transistors in Tissue-Interfaced Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Investigation of Transport in OECTs with Electrochemical Strain Wave Microscopy.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- A one-transistor organic electrochemical self-sustained oscillator model for neuromorphic networks.Newton ((New York, N.Y.) · 2025Article
- Organic Electrochemical Transistors Monolithically Integrated with Precise Micro-Dispensing Enable High-Performance Biosignals Amplification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Dissipative charge transport in organic mixed ionic-electronic conductor channels.Nature communications · 2025Article
- Using the Transversal Admittance to Understand Organic Electrochemical Transistors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Organic electro-scattering antenna: Wireless and multisite probing of electrical potentials with high spatial resolution.Science advances · 2024Article
- Small signal analysis for the characterization of organic electrochemical transistors.Nature communications · 2024Article
- Organic Electrochemical Transistors for Biomarker Detections.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Ionic Solvent Shell Drives Electroactuation in Organic Mixed Ionic-Electronic Conductors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- In Vitro Models for Investigating Intestinal Host-Pathogen Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Hysteresis in Organic Electrochemical Transistors: Distinction of Capacitive and Inductive Effects.The journal of physical chemistry letters · 2023Article
- Experimental design of stencil-printed high-performance organic electrochemical transistors.Materials advances · 2023Article
- Efficient N-Type Organic Electrochemical Transistors and Field-Effect Transistors Based on PNDI-Copolymers Bearing Fluorinated Selenophene-Vinylene-Selenophenes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Organic electrochemical transistors as on-site signal amplifiers for electrochemical aptamer-based sensing.Nature communications · 2023Article
- Organic Bioelectronics Development in Italy: A Review.Micromachines · 2023Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research on electrolyte-gated and organic electrochemical transistor (OECT) architectures is motivated by the prospect of a highly biocompatible interface capable of amplifying bioelectronic signals at the site of detection. Despite many demonstrations in these directions, a quantitative model for OECTs as impedance biosensors is still lacking. We overcome this issue by introducing a model experiment where we simulate the detection of a single cell by the impedance sensing of a dielectric microparticle. The highly reproducible experiment allows us to study the impact of transistor geometry and operation conditions on device sensitivity. With the data we rationalize a mathematical model that provides clear guidelines for the optimization of OECTs as single cell sensors, and we verify the quantitative predictions in an in-vitro experiment. In the optimized geometry, the OECT-based impedance sensor allows to record single cell adhesion and detachment transients, showing a maximum gain of 20.2±0.9 dB with respect to a single electrode-based impedance sensor.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.