Evidence map›Paper›PMID 36109445›Full record

ArticleThe international journal of cardiovascular imaging2023

Validation of a semi-automatic software for optical coherence tomography - analysis in heart transplanted patients.

Niels Møller Jensen, Zhi Chen, Tor Skibsted Clemmensen, Omeed Neghabat, Emil Nielsen Holck, Michal Pazdernik, Lone Juul Hune Mogensen, Andreas Wahle, Milan Sonka, Hans Eiskjær

Open access · goldAbstract read
In one paragraph

Article in The international journal of cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Niels Møller JensenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, entrance F, Aarhus, Denmark. nimoje@rm.dk.ORCID http://orcid.org/0000-0002-5009-5955
Zhi ChenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Tor Skibsted ClemmensenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, entrance F, Aarhus, Denmark.
Omeed NeghabatDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, entrance F, Aarhus, Denmark.
Emil Nielsen HolckDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, entrance F, Aarhus, Denmark.
Michal PazdernikDepartment of Cardiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Lone Juul Hune MogensenDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, entrance F, Aarhus, Denmark.
Andreas WahleDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Milan SonkaDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Hans EiskjærDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, entrance F, Aarhus, Denmark.
University of Iowa · USAarhus University · DKAarhus University Hospital · DKInstitute of Clinical and Experimental Medicine · CZ

Funding

Graph-Based Medical Image Segmentation in 3D and 4DR01EB004640 · NIBIB · UNIVERSITY OF IOWA · PI BUATTI, JOHN M, SONKA, MILAN · 2006 to 2022
$6.1M
NIBIB NIH HHS R01 EB004640
6 · The paper itself

Abstract

Optical Coherence Tomography (OCT) is an intravascular imaging modality enabling detailed evaluation of cardiac allograft vasculopathy (CAV) after heart transplantation (HTx). However, its clinical application remains hampered by time-consuming manual quantitative analysis. We aimed to validate a semi-automated quantitative OCT analysis software (Iowa Coronary Wall Analyzer, ICWA-OCT) to improve OCT-analysis in HTx patients. 23 patients underwent OCT evaluation of all three major coronary arteries at 3 months (3M) and 12 months (12M) after HTx. We analyzed OCT recordings using the semiautomatic software and compared results with measurements from a validated manual software. For semi-automated analysis, 31,228 frames from 114 vessels were available. The validation was based on a subset of 4287 matched frames. We applied mixed model statistics to accommodate the multilevel data structure with method as a fixed effect. Lumen (minimum, mean, maximum) and media (mean, maximum) metrics showed no significant differences. Mean and maximum intima area were underestimated by the semi-automated method (β-method

Indexed as

Coronary Artery DiseaseHeart DiseasesHeart TransplantationCoronary VesselsHumansPredictive Value of TestsSoftwareTomography, Optical CoherenceCardiac allograft vasculopathyHeart transplantationIntravascular imagingOptical coherence tomographyValidation

Identifiers

PMID36109445
PMCPMC10519345
OpenAlexW4296028487

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.