ArticleThorax2023
Reduced lung function and health-related quality of life after treatment for pulmonary tuberculosis in Gambian children: a cross-sectional comparative study.
Article in Thorax, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Prevalence and associated factors of post-tuberculosis lung disease in Sub-Saharan Africa: a systematic review and meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Post-pulmonary tuberculosis lung function: a systematic review and meta-analysis.The Lancet. Global health · 2025Pooled it
- Post-Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management.MedComm · 2026Review
- Long term outcome following pulmonary TB or lower respiratory tract illness in children: a prospective South African study.EClinicalMedicine · 2026Article
- "Once you get TB, life changes": post-tuberculosis experiences and care needs in East Africa.IJTLD chronic respiratory disease · 2026Article
- Pediatric Tuberculosis: Unraveling Immunity, Clinical Complexities, and Resource-Driven Disparities in the Pursuit of Prevention.Vaccines · 2026Review
- An integrative genetic and transcriptomic study reveals a causal link and candidate biomarkers between tuberculosis and asthma.Frontiers in genetics · 2026Article
- Lung function impairment in children post-tuberculosis treatment: a systematic review and meta-analysis.Frontiers in pediatrics · 2026Review
- Multimorbidity and health-related quality of life after tuberculosis treatment in Zimbabwe: A cross-sectional study with household comparators.PLOS global public health · 2026Article
- Proceedings from the Third International Post-Tuberculosis Symposium: expanding the circle.IJTLD open · 2025Article
- Post-TB treatment completion experiences of children, adolescents, and caregivers from Cape Town.IJTLD open · 2025Article
- Lung function trajectories in children with pulmonary TB and non-TB lower respiratory tract infections.IJTLD open · 2025Article
- Article
- Post-tuberculosis lung disease: towards prevention, diagnosis, and care.The Lancet. Respiratory medicine · 2025Review
- Article
- Tuberculosis-associated respiratory impairment and disability in children and adolescents: a systematic review.EClinicalMedicine · 2025Article
- Sequelae of Immunocompromised Host Pneumonia.Clinics in chest medicine · 2025Review
- Anthropometric growth trajectories of children presenting with presumptive pulmonary TB.IJTLD open · 2025Article
- "I live with pain, it cannot go away": Lived experiences of childhood and adolescent pulmonary tuberculosis survivors - a qualitative study.PLOS global public health · 2025Article
- Post-TB sequelae in adolescent pulmonary TB survivors.IJTLD open · 2025Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundPost-tuberculosis (post-TB) lung disease is an under-recognised consequence of pulmonary tuberculosis (pTB). We aimed to estimate the prevalence of residual lung function impairment and reduced health-related quality of life (HRQoL) in children after pTB treatment completion.
methodsWe conducted a cross-sectional comparative study of children aged less than 15 years at TB diagnosis who had completed treatment for pTB at least 6 months previously with a comparator group of age-matched children without a history of pTB. Symptoms, spirometry and HRQoL measured with PedsQL scale were collected. Variables associated with lung function impairment were identified through logistic regression models.
resultsWe enrolled 68 post-TB cases (median age 8.9 (IQR 7.2-11.2) years) and 91 children in the comparison group (11.5 (8.0-13.7) years). Spirometry from 52 (76.5%) post-TB cases and 89 (94.5%) of the comparison group met the quality criteria for acceptability and repeatability. Lung function impairment was present in 20/52 (38.5%) post-TB cases and 15/86 (17.4%) in the comparison group, p=0.009. Previous pTB and a history of chronic cough were significantly associated with the presence of lung function impairment (p=0.047 and 0.006 respectively). Forced expiratory volume in 1 s (FEV
conclusionsPrevious TB in children is associated with significantly impaired lung function and HRQoL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.