Evidence map›Paper›PMID 36109035›Full record

ArticleBMJ open2022

MiCare study, an evaluation of structured, multidisciplinary and personalised post-ICU care on physical and psychological functioning, and quality of life of former ICU patients: a study protocol of a stepped-wedge cluster randomised controlled trial.

Dries van Sleeuwen, Floris A van de Laar, Koen Simons, Daniëlle van Bommel, Dominique Burgers-Bonthuis, Julia Koeter, Laurens L A Bisschops, Lilian Vloet, Marianne Brackel, Steven Teerenstra and 4 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05066984 (Evaluation of Structured, Multidisciplinary and Personalized Post-ICU Care on Physical and Psychological Functioning, and Quality of Life of Former ICU Patients), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05066984 naactive not recruitingnot on this map

Evaluation of Structured, Multidisciplinary and Personalized Post-ICU Care on Physical and Psychological Functioning, and Quality of Life of Former ICU Patients

TypeinterventionalSponsorRadboud University Medical CenterRan2022 to 2027Enrolled2,250ConditionsPost ICU SyndromeArmsstructured, multidisciplinary and personalized post-ICU care
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dries van SleeuwenIntensive Care, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0003-0431-3218
Floris A van de LaarPrimary care and community care, Radboud University Medical Center, Nijmegen, The Netherlands.
Koen SimonsIntensive Care, Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands.ORCID 0000-0001-8120-5566
Daniëlle van BommelIntensive Care, Bernhoven Hospital, Uden, The Netherlands.
Dominique Burgers-BonthuisIntensive Care, Rijnstate Hospital, Arnhem, The Netherlands.
Julia KoeterIntensive Care, Canisius Wilhelmina Ziekenhuis, Nijmegen, The Netherlands.
Laurens L A BisschopsIntensive Care, Radboud University Medical Center, Nijmegen, The Netherlands.
Lilian VloetEmergency and Critical Care, HAN University of Applied Sciences, Nijmegen, The Netherlands.
Marianne BrackelFCIC (Family and Patient Centered Intensive Care) Foundation, Alkmaar, The Netherlands.
Steven TeerenstraHealth Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Eddy AdangHealth Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Johannes G van der HoevenIntensive Care, Radboud University Medical Center, Nijmegen, The Netherlands.
Marieke ZegersIntensive Care, Radboud University Medical Center, Nijmegen, The Netherlands marieke.zegers@radboudumc.nl.ORCID 0000-0002-7472-6184
Mark van den BoogaardIntensive Care, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0003-4233-2903

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOver 70% of the intensive care unit (ICU) survivors suffer from long-lasting physical, mental and cognitive problems after hospital discharge. Post-ICU care is recommended by international guidelines, but evidence for cost-effectiveness lacks. The aim of this study is to evaluate the clinical effectiveness and cost-effectiveness of structured, multidisciplinary and personalised post-ICU care versus usual care on physical and psychological functioning and health-related quality of life (HRQoL) of ICU survivors, 1- and 2-year post-ICU discharge. METHODS AND ANALYSIS: The MONITOR-IC post-ICU care study (MiCare study) is a multicentre stepped-wedge randomised controlled trial conducted in five hospitals. Adult patients at high risk for critical illness-associated morbidity post-ICU will be selected and receive post-ICU care, including an invitation to the post-ICU clinic 3 months after ICU discharge. A personalised long-term recovery plan tailored to patients' reported outcome measures will be made. 770 (intervention) and 1480 (control) patients will be included. Outcomes are 1- and 2-year HRQoL (EuroQol Instrument (EQ-5D-5L)), physical (fatigue and new physical problems), mental (anxiety, depression and post-traumatic stress disorder), and cognitive symptoms and cost-effectiveness. Medical data will be retrieved from patient records and cost data from health insurance companies. ETHICS AND DISSEMINATION: Due to the lack of evidence, Dutch healthcare insurers do not reimburse post-ICU care. Therefore, evaluation of cost-effectiveness and integration in guidelines supports the evidence. Participation of several societies for physicians, nurses, paramedics, and patients and relatives in the project team increases the support for implementation of the intervention in clinical practice. Patients and relatives will be informed by the patient associations, hospitals and professional associations. Informing healthcare insurers about this project's results is important for the consideration for inclusion of post-ICU care in Dutch standard health insurance. The study is approved by the Radboud University Medical Centre research ethics committee (2021-13125). TRIAL REGISTRATION NUMBER: NCT05066984.

Indexed as

Intensive Care UnitsQuality of LifeAdultCritical CareCritical IllnessHumansMulticenter Studies as TopicRandomized Controlled Trials as TopicSurveys and Questionnairesadult intensive and critical careintensive and critical careprimary careprotocols and guidelines

Identifiers

PMID36109035
PMCPMC9478839

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.