Evidence map›Paper›PMID 36108975›Full record

ArticleInfectious diseases now2022

SARS-CoV-2 seroprevalence and antibodies persistence among health care workers after the first COVID-19 wave in nine hospitals in Western France.

R Garlantezec, E Tadié, C Heslan, P Gary-Bobo, S Oumari, A Saade, A Sitruk, P Tattevin, V Thibault, C Paris and 1 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Infectious diseases now, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04416308 (COVID 19), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04416308 nacompletednot on this map

COVID 19 : Seroprevalence Study of Anti SRAS-CoV-2 Antibodies in GHT Employees in Haute Bretagne

TypeinterventionalSponsorRennes University HospitalRan2020 to 2020Enrolled9,453ConditionsCoronavirusArmsNG test, Blood test, Self-questionnary
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

R GarlantezecCHU de Rennes, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France. Electronic address: ronan.garlantezec@chu-rennes.fr.
E TadiéCHU de Rennes, F-35000 Rennes, France.
C HeslanCHU de Rennes, F-35000 Rennes, France.
P Gary-BoboCHU de Rennes, F-35000 Rennes, France.
S OumariCHU de Rennes, F-35000 Rennes, France.
A SaadeCHU de Rennes, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France.
A SitrukCHU de Rennes, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France.
P TattevinCHU de Rennes, Univ Rennes, INSERM U1230, IFR140, F-35033 Rennes, France.
V ThibaultCHU de Rennes, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France.
C ParisCHU de Rennes, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France.
AntiCOV-HB* working group
Inserm · FRCentre Hospitalier Universitaire de Rennes · FRCentre Hospitalier de Fougères · FRCentre Hospitalier de Vitré · FRCentre Hospitalier de Redon · FRCentre Hospitalier de Rochefort · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate the SARS-CoV-2 IgG seroprevalence rate in healthcare workers (HCWs) from Western France after the first 2020 wave, its determinants and the kinetics of total SARS-CoV-2 antibodies. PATIENTS AND

methodsOverall, 9,453 HCWs responded to a self-questionnaire and underwent a lateral flow immunoassay to assess SARS-CoV-2 IgG presence. For 72 HCWs who tested positive, total anti-nucleocapsid antibodies were assessed at day 0, 30, and 90.

resultsSARS-CoV-2 IgG seroprevalence rate was 1.06 % [0.86 %-1.27 %]. Factors associated with IgG presence were gender, performing upper respiratory tract samples, contact with HCWs or household members diagnosed with COVID-19. Total antibodies decreased between day 0 and day 90, with anosmia or ageusia, and were higher in HCWs older than 50 years.

conclusionWe reported a low prevalence rate of IgG and identified several risk factors associated with its presence and persistence of total antibodies. Additional studies are needed to confirm these observations.

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralHealth PersonnelHospitalsHumansImmunoglobulin GSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin GHealth care workersOccupational exposureSARS-CoV-2Seroprevalence survey

Identifiers

PMID36108975
PMCPMC9467933
OpenAlexW4296015352

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.