Evidence map›Paper›PMID 36108258›Full record

ArticleJCO precision oncology2022

Universal Germline Genetic Testing for Hereditary Cancer Syndromes in Patients With Solid Tumor Cancer.

Edward D Esplin, Sarah M Nielsen, Sara L Bristow, Judy E Garber, Heather Hampel, Huma Q Rana, N Jewel Samadder, Neal D Shore, Robert L Nussbaum

Abstract read
In one paragraph

Article in JCO precision oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. [Genetic diagnostics].Pathologie (Heidelberg, Germany) · 2026
    Review
  4. BRCA Testing in Asian Patients with Ovarian Cancer: Standard Clinical Practice or Mutation Prediction Model?Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  5. Article
  6. Review
  7. A scalable new model of germline cancer genomic care delivery: Assessing psychological outcomes.Genetics in medicine : official journal of the American College of Medical Genetics · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. JTO clinical and research reports · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Edward D EsplinInvitae, San Francisco, CA.ORCID 0000-0001-9205-3756
Sarah M NielsenInvitae, San Francisco, CA.ORCID 0000-0002-5916-6393
Sara L BristowInvitae, San Francisco, CA.ORCID 0000-0002-1173-4718
Judy E GarberDana Farber Cancer Institute, Boston, MA.ORCID 0000-0001-9449-3982
Heather HampelDivision of Clinical Cancer Genomics, Department of Medical Oncology & Therapeutic Research, City of Hope National Cancer Center, Duarte, CA.ORCID 0000-0001-7558-9794
Huma Q RanaDana Farber Cancer Institute, Boston, MA.ORCID 0000-0002-1598-6752
N Jewel SamadderCenter for Individualized Medicine, Mayo Clinic, Phoenix, AZ.ORCID 0000-0001-7182-5569
Neal D ShoreCarolina Urologic Research Center, Myrtle Beach, SC.ORCID 0000-0001-5767-0548
Robert L NussbaumInvitae, San Francisco, CA.ORCID 0000-0003-3445-8880

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neoplastic Syndromes, HereditaryGenetic TestingGerm CellsHumans

Identifiers

PMID36108258
PMCPMC9489188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.