Evidence map›Paper›PMID 36108052›Full record

ArticleAmerican journal of physiology. Renal physiology2022

Regulation of glomerulotubular balance. IV. Implication of aquaporin 1 in flow-dependent proximal tubule transport and cell volume.

Zhaopeng Du, Qingshang Yan, Emma Shen, Alan M Weinstein, Tong Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Flow-dependent transport processes 2024: filtration, absorption, and secretion.American journal of physiology. Renal physiology · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhaopeng DuDepartment of Cellular and Molecular Physiology, Yale University, New Haven, Connecticut.
Qingshang YanDepartment of Cellular and Molecular Physiology, Yale University, New Haven, Connecticut.
Emma ShenDepartment of Cellular and Molecular Physiology, Yale University, New Haven, Connecticut.
Alan M WeinsteinDepartment of Physiology and Biophysics, Weill Medical College, Cornell University, New York, New York.ORCID 0000-0002-3192-1297
Tong WangDepartment of Cellular and Molecular Physiology, Yale University, New Haven, Connecticut.ORCID 0000-0001-7054-2540
Yale University · USCornell University · US

Funding

THEORY OF SOLUTE AND WATER TRANSPORT ACROSS EPITHELIAR01DK029857 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI WEINSTEIN, ALAN M · 1986 to 2022
$3.8M
Defective flow-dependent tubule transport in the pathogenesis of kidney diseaseR01DK117650 · NIDDK · YALE UNIVERSITY · PI WANG, TONG WANG · 2019 to 2022
$1.5M
NIDDK NIH HHS R01 DK029857NIDDK NIH HHS R01 DK117650
6 · The paper itself

Abstract

The water channel aquaporin-1 (AQP1) is the principal water pathway for isotonic water reabsorption in the kidney proximal tubule (PT). We investigated flow-mediated fluid (

Indexed as

Aquaporin 1Kidney Tubules, ProximalAnimalsCell SizeMiceMice, KnockoutRatsWaterAquaporin 1Wateraquaporin 1 knockout mousebicarbonate transportflow-dependent transportglomerulotubular balancemicroperfusion

Identifiers

PMID36108052
PMCPMC9705020
OpenAlexW4296036668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.