Evidence map›Paper›PMID 36107991›Full record

Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2022

A multi-trial, retrospective analysis of the antihypertensive effects of high-resistance, low-volume inspiratory muscle strength training.

Daniel H Craighead, Dallin Tavoian, Kaitlin A Freeberg, Josie L Mazzone, Jennifer R Vranish, Claire M DeLucia, Douglas R Seals, E Fiona Bailey

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05643768 (Effects of Inspiratory Muscle Strength Training on Metabolic and Cardiovascular Health in Adults With Type 2 Diabetes), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05643768 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Inspiratory Muscle Strength Training on Metabolic and Cardiovascular Health in Adults With Type 2 Diabetes

TypeinterventionalSponsorUniversity of ArizonaRan2023 to 2024Enrolled11ConditionsDiabetes Mellitus, Type 2, HypertensionArmsInspiratory muscle strength training (IMST)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Prognostic value of exercise blood pressure: role of fitness and exercise training.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Daniel H CraigheadDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado.ORCID 0000-0002-8744-5349
Dallin TavoianDepartment of Physiology, University of Arizona College of Medicine, Tucson, Arizona.ORCID 0000-0003-3146-8944
Kaitlin A FreebergDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado.
Josie L MazzoneDepartment of Physiology, University of Arizona College of Medicine, Tucson, Arizona.
Jennifer R VranishDepartment of Integrative Physiology and Health Science, Alma College, Alma, Michigan.ORCID 0000-0002-4252-6639
Claire M DeLuciaDepartment of Physiology, University of Arizona College of Medicine, Tucson, Arizona.ORCID 0000-0002-1626-4348
Douglas R SealsDepartment of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado.ORCID 0000-0002-2391-9824
E Fiona BaileyDepartment of Physiology, University of Arizona College of Medicine, Tucson, Arizona.ORCID 0000-0001-5683-7107
University of Arizona · USUniversity of Colorado Boulder · USAlma College · US

Funding

PHYSIOLOGYT32HL007249 · NHLBI · UNIVERSITY OF ARIZONA · PI Brett A Colson, JOHN P KONHILAS · 1985 to 2026
$12.5M
Time-efficient inspiratory muscle strength training for improving blood pressure and vascular function in older adults with sleep-disordered breathingR01AG065346 · NIA · UNIVERSITY OF ARIZONA · PI BAILEY, E. FIONA · 2020 to 2025
$3.4M
Novel time-efficient inspiratory muscle strength training for lowering systolic blood pressure and improving endothelial, cerebrovascular, and cognitive functionK01HL153326 · NHLBI · UNIVERSITY OF MINNESOTA · PI CRAIGHEAD, DANIEL HARRISON · 2020 to 2024
$899k
Inspiratory muscle strength training for lowering blood pressure in hypertensive mid-life adultsR21AG061677 · NIA · UNIVERSITY OF COLORADO · PI SEALS, DOUGLAS R · 2019 to 2020
$606k
Nicotinamide Riboside Supplementation for Decreasing Inflammation in Middle-Aged and Older AdultsF31HL154782 · NHLBI · UNIVERSITY OF COLORADO · PI FREEBERG, KAITLIN · 2020 to 2022
$115k
American Heart Association-American Stroke Association 18POST33990034NHLBI NIH HHS F31 HL154782NHLBI NIH HHS K01 HL153326NHLBI NIH HHS T32 HL007249NIA NIH HHS R01 AG065346NIA NIH HHS R21 AG061677
6 · The paper itself

Abstract

Above-normal blood pressure (BP) is a primary risk factor for cardiovascular diseases. In a retrospective analysis of five pilot trials, we assessed the BP-lowering effects of high-resistance inspiratory muscle strength training (IMST) in adults aged 18-82 years and the impact of IMST on maximal inspiratory pressure (PI

Indexed as

HypertensionResistance TrainingAdolescentAdultAgedAged, 80 and overAntihypertensive AgentsBlood PressureFemaleHumansMaleMiddle AgedMuscle StrengthRespiratory MusclesRetrospective StudiesYoung AdultAntihypertensive Agentsblood pressuremaximal inspiratory pressuretime-efficient

Identifiers

PMID36107991
PMCPMC9550580
OpenAlexW4296036005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.