Evidence map›Paper›PMID 36107868›Full record

ArticlePloS one2022

Study of pulsed electrostatic field (PESF) in the perfusion of peripheral tissues: Microangiopathy, nutrition and quality of perceiver life.

Rossella Liani, Sara La Torre, Valentina Liani, Angela Melchiorre, Danilo D'Ettorre, Romina Tripaldi, Stefano Lattanzio, Rossano Di Luzio, Mauro Coli, Carlo Velussi

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rossella LianiDepartment of Medicine and Aging, CAST_Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, Chieti, Italy.ORCID 0000-0002-1523-530X
Sara La TorreDepartment of Medicine and Aging, CAST_Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, Chieti, Italy.
Valentina LianiNephrology and Dialysis Unit, "S. Massimo" Hospital, Penne, Italy.
Angela MelchiorreNephrology and Dialysis Unit, "S. Massimo" Hospital, Penne, Italy.
Danilo D'EttorreNephrology and Dialysis Unit, "S. Massimo" Hospital, Penne, Italy.
Romina TripaldiDepartment of Medicine and Aging, CAST_Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, Chieti, Italy.
Stefano LattanzioDepartment of Medicine and Aging, CAST_Center for Advanced Studies and Technology, University G. d'Annunzio of Chieti-Pescara, Chieti, Italy.
Rossano Di LuzioNephrology and Dialysis Unit, "S. Massimo" Hospital, Penne, Italy.
Mauro ColiDepartment of Economics, Institute of Statistics, University of Chieti, Chieti, Italy.
Carlo VelussiRetired Associate Professor of Physiology, University of Padova, Padova, Italy.
University of Chieti-Pescara · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microangiopathy compromises the structural and functional integrity of organs and tissues in patients with type II diabetes mellitus (T2DM) negatively affecting the perceived quality of life. Nitric oxide (NO) is a multifunctional signalling molecule, acting as a vasodilator, neurotransmitter, and modulator of inflammatory processes. Patients with type II diabetes mellitus and chronic kidney disease, controlled from glycaemic status, were treated or not with pulsed electrostatic field (PESF) cycles to evaluate effect on the perfusion of peripheral tissues. Everyone was monitored for the metabolic profile, and we tested circulating NO with a commercial enzyme immunoassay kit. In addition, we tested the perceived quality of life of patients before/after a PESF cycle using a questionnaire. Patients treated with PESF were improved circulating NO levels, significant changes in systolic and diastolic blood pressure, heart rate and were more homogeneous for their metabolic profile. The questionnaire showed also a marked improvement in the perceived quality of life. The use of pulsed electrostatic fields has allowed us to observe an improvement in the metabolic, psychological, and clinical profile in patients with T2DM and chronic kidney disease whose pathological profile is strongly compromised.

Indexed as

Diabetes Mellitus, Type 2Renal Insufficiency, ChronicVascular DiseasesHumansNitric OxidePerfusionQuality of LifeStatic ElectricityVasodilator AgentsNitric OxideVasodilator Agents

Identifiers

PMID36107868
PMCPMC9477350
OpenAlexW4295901390

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.