Evidence map›Paper›PMID 36107594›Full record

ReviewMedicine2022

Diagnosis and treatment of tuberculosis in adults with HIV.

Qiaoli Yang, Jinjin Han, Jingjing Shen, Xinsen Peng, Lurong Zhou, Xuejing Yin

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06531772 (Characteristics and Outcomes of TB and HIV Co-infections), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06531772 unknown statusnot on this mapstarted 2023, after this paper: background citation

Characteristics and Outcomes of TB and HIV Co-infections

TypeobservationalSponsorAssiut UniversityRan2023 to 2025Enrolled100ConditionsHuman Immunodeficiency Virus, Mycobacterium TuberculosisArmsAntitubercular Agents
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Qiaoli YangDepartment of Infectious Diseases, Changzhi Medical College, Changzhi, Shanxi Province, China.
Jinjin HanDepartment of Infectious Diseases, Changzhi Medical College, Changzhi, Shanxi Province, China.
Jingjing ShenDepartment of Infectious Diseases, Changzhi people's Hospital, Changzhi, Shanxi Province, China.
Xinsen PengDepartment of Cardiology, Changzhi Medical College, Changzhi, Shanxi Province, China.
Lurong ZhouDepartment of Infectious Diseases, Changzhi Medical College, Changzhi, Shanxi Province, China.ORCID 0000-0003-3370-14710000-0003-3370-1471
Xuejing YinDepartment of Neurology, Changzhi Medical College, Changzhi, Shanxi Province, China.
Changzhi Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), continues to pose a major public health problem and is the leading cause of mortality in people infected with human immunodeficiency virus (HIV). HIV infection greatly increases the risk of developing TB even before CD4+ T-cell counts decrease. Co-infection provides reciprocal advantages to both pathogens and leads to acceleration of both diseases. In HIV-coinfected persons, the diagnosis and treatment of tuberculosis are particularly challenging. Intensifying integration of HIV and tuberculosis control programmes has an impact on reducing diagnostic delays, increasing early case detection, providing prompt treatment onset, and ultimately reducing transmission. In this Review, we describe our current understanding of how these two pathogens interact with each other, new sensitive rapid assays for TB, several new prevention methods, new drugs and regimens.

Indexed as

CoinfectionHIV InfectionsMycobacterium tuberculosisTuberculosisAdultCD4-Positive T-LymphocytesHumans

Identifiers

PMID36107594
PMCPMC9439776
OpenAlexW4294301102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.