Evidence map›Paper›PMID 36107524›Full record

ArticleMedicine2022

Clinical features and characteristics of pediatric patients with COVID-19 infection: Experiences in a Tertiary Taiwan Hospital.

Geng-Hao Bai, Ping-Yi Shih, Shih-Yen Chen, Kai-Sheng Hsieh, Cheng-Che Chou, Po-Hao Feng, Shu-Sing Kong, Wen-Chuan Lin, Meng-Che Lu

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Geng-Hao BaiDepartment of Education, National Taiwan University Hospital, Taipei city, Taiwan.
Ping-Yi ShihDepartment of Pediatrics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Shih-Yen ChenDepartment of Pediatrics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Kai-Sheng HsiehDepartment of Pediatrics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Cheng-Che ChouDepartment of Pediatrics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Po-Hao FengDivision of Pulmonary Medicine, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Shu-Sing KongDepartment of Pediatrics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Wen-Chuan LinDepartment of Pediatrics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Meng-Che LuDepartment of Pediatrics, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.ORCID 0000-0002-9170-54140000-0002-9170-5414
Zero to Three · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) patients have distinct clinical features in the pediatric groups. However, there is a paucity of research focused on clinical manifestation within pediatric group in Taiwan. This study is to conduct a retrospective study of the clinical features of COVID-19 in Taiwan pediatric patients. A retrospective study was conducted on pediatric patients (Aged ≤ 18 years) in a Northern Taiwan hospital from May 1st, 2021 to June 30th, 2021. Thirty-eight patients were included from emergency room. They were laboratory confirmed COVID-19 through specimens from nasopharyngeal swab by real-time reverse-transcription polymerase chain reaction (RT-PCR). Data including RT-PCR cycle threshold (Ct) values, clinical and epidemiological features were collected and analyzed. Thirty-eight patients aged from 7-month to 18-year-old were included. The median age of patients was 15-year-old. The patients had sex ratio of 23 males to 15 females. More than half patients were infected from family members. Asymptomatic patients were 47.37%. In the symptomatic patients, fever (34.21%) was the most predominant symptom. Cough, nasal obstruction and sore throat were also common. Asymptomatic children had significantly higher Ct-values than symptomatic children, and diagnosed patients with Ct-values more than 19 were associated with asymptomatic infection (P = .0084). Ct-values higher than 19 were associated with asymptomatic infection, which may be a predictor of pediatric disease severity. Our results highlight the distinct clinical manifestations and outcomes in pediatric COVID-19 patients. Compared to the adults, pediatric patients aged ≤ 18 years with COVID-19 in Taiwan mainly had mild disease.

Indexed as

COVID-19AdolescentAdultAsymptomatic InfectionsChildFemaleHumansMaleRetrospective StudiesTaiwanTertiary Care Centers

Identifiers

PMID36107524
PMCPMC9439632
OpenAlexW4294300989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.