Evidence map›Paper›PMID 36107451›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023

The SIDECAR project: S-IcD registry in European paediatriC and young Adult patients with congenital heaRt defects.

Massimo Stefano Silvetti, Luc Bruyndonckx, Alice Maltret, Roman Gebauer, Joanna Kwiatkowska, László Környei, Sonia Albanese, Cristina Raimondo, Christian Paech, Maciej Kempa and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Early complications and long-term outcomes of patients treated with a subcutaneous cardioverter-defibrillator: temporal trends and clinical implications of the anaesthetic strategies adopted at implant.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Observational
  4. Review
  5. Article
  6. Outcomes for patients implanted with a cardioverter-defibrillator at <19 years of age: a Swedish national study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  7. The SIDECAR 2.0 (S-ICD registry in European paediatric and young adult patients with congenital heart defects 2.0): an analysis of European S-ICD clinical practice and its evolution in paediatric patients.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Observational
  8. Review
  9. Review
  10. Implantable cardioverter defibrillator therapy in paediatric patients for primary vs. secondary prevention.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  11. Review
  12. Advancing the science of management of arrhythmic disease in children and adult congenital heart disease patients within the last 25 years.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Review
  13. S-ICD Implantation "Tips and Tricks".Reviews in cardiovascular medicine · 2023
    Review
  14. The R″ wave in V1 and the negative terminal QRS vector in aVF combine to a novel 12-lead ECG algorithm to identify slow conducting anatomical isthmus 3 in patients with tetralogy of Fallot.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 7 countries.

Massimo Stefano SilvettiPaediatric Cardiology and Cardiac Arrhythmia/Syncope Unit, Department of Paediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.ORCID 0000-0001-9284-5972
Luc BruyndonckxDepartment of Paediatric Cardiology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.ORCID 0000-0002-2315-9925
Alice MaltretDepartment of Paediatric Cardiology Hopital Necker-Enfants Malades, Paris, France.ORCID 0000-0001-9934-6746
Roman GebauerDepartment of Paediatric Cardiology, Heart Centre Leipzig, University of Leipzig, Leipzig, Germany.
Joanna KwiatkowskaDepartment of Paediatric Cardiology and Congenital Heart Defects, Medical University of Gdansk, Gdansk, Poland.ORCID 0000-0001-9760-1977
László KörnyeiGottsegen National Cardiovascular Center, Budapest, Hungary.ORCID 0000-0001-7012-6133
Sonia AlbaneseHeart Surgery Team, Department of Paediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.ORCID 0000-0002-9064-6651
Cristina RaimondoPaediatric Cardiology and Cardiac Arrhythmia/Syncope Unit, Department of Paediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.ORCID 0000-0002-3100-2493
Christian PaechDepartment of Paediatric Cardiology, Heart Centre Leipzig, University of Leipzig, Leipzig, Germany.ORCID 0000-0001-9676-8994
Maciej KempaDepartment of Cardiology and Electrotherapy, Medical University of Gdansk, Gdansk, Poland.ORCID 0000-0002-3472-2883
Gábor FésüsGottsegen National Cardiovascular Center, Budapest, Hungary.ORCID 0000-0001-9328-6295
Reinoud E KnopsDepartment of Paediatric Cardiology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Nico Andreas BlomDepartment of Paediatric Cardiology, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Fabrizio DragoPaediatric Cardiology and Cardiac Arrhythmia/Syncope Unit, Department of Paediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.ORCID 0000-0003-1888-373X
Bambino Gesù Children's Hospital · ITGdańsk Medical University · PLGottsegen National Cardiovascular Center · HUHôpital Necker-Enfants Malades · FRLeipzig Heart Institute · DEAntwerp University Hospital · BELeiden University Medical Center · NLUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsSubcutaneous-implantable cardiac defibrillators (S-ICDs) are used increasingly to prevent sudden cardiac death in young patients. This study was set up to gain insight in the indications for S-ICD, possible complications, and their predictors and follow-up results. METHODS AND

resultsA multicentre, observational, retrospective, non-randomized, standard-of-care registry on S-ICD outcome in young patients with congenital heart diseases (CHDs), inherited arrhythmias (IAs), idiopathic ventricular fibrillation (IVF), and cardiomyopathies (CMPs). Anthropometry was registered as well as implantation technique, mid-term device-related complications, and incidence of appropriate/inappropriate shocks (IASs). Data are reported as median (interquartile range) or mean ± standard deviation. Eighty-one patients (47% CMPs, 20% CHD, 21% IVF, and 12% IA), aged 15 (14-17) years, with body mass index (BMI) 21.8 ± 3.8 kg/m2, underwent S-ICD implantation (primary prevention in 59%). This was performed with two-incision technique in 81% and with a subcutaneous pocket in 59%. Shock and conditional zones were programmed at 250 (200-250) and 210 (180-240) b.p.m., respectively. No intraoperative complications occurred. Follow up was 19 (6-35) months: no defibrillation failure occurred, 17% of patients received appropriate shocks, 13% of patients received IAS (supraventricular tachycardias 40%, T-wave oversensing 40%, and non-cardiac oversensing 20%). Reprogramming, proper drug therapy, and surgical revision avoided further IAS. Complications requiring surgical revision occurred in 9% of patients, with higher risks in patients with three-incision procedures [hazard ratio (HR) 4.3, 95% confidence interval (95% CI) 0.5-34, P = 0.038] and BMI < 20 (HR 5.1, 95% CI 1-24, P = 0.031).

conclusionThis multicentre European paediatric registry showed good S-ICD efficacy and safety in young patients. Newer implantation techniques and BMI > 20 showed better outcome.

Indexed as

Defibrillators, ImplantableHeart Defects, CongenitalArrhythmias, CardiacChildDeath, Sudden, CardiacHumansRegistriesRetrospective StudiesTreatment OutcomeVentricular FibrillationYoung AdultCongenital heart diseaseICD complicationsImplantable cardioverter defibrillatorPaediatric ageSubcutaneous-ICD

Identifiers

PMID36107451
PMCPMC9935000
OpenAlexW4295908428

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.