Evidence map›Paper›PMID 36107389›Full record

ArticleCancer medicine2023

Mortality after the 9/11 terrorist attacks among world trade center health registry enrollees with cancer.

Rebecca D Kehm, Jiehui Li, Erin Takemoto, Janette Yung, Baozhen Qiao, Mark R Farfel, James E Cone

Abstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rebecca D KehmNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.
Jiehui LiNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.ORCID 0000-0002-7812-8878
Erin TakemotoNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.
Janette YungNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.
Baozhen QiaoNew York State Department of Health, Bureau of Cancer Epidemiology, Albany, New York, USA.
Mark R FarfelNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.
James E ConeNew York City Department of Health and Mental Hygiene, World Trade Center Health Registry, Long Island City, New York, USA.

Funding

Extension of the World Trade Center RegistryU50OH009739 · OH · NEW YORK CITY HEALTH/MENTAL HYGIENE · PI FARFEL, MARK R · 2009 to 2025
$120.0M
NCCDPHP CDC HHS NU58DP006344NCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INIOSH CDC HHS U50 OH009739
6 · The paper itself

Abstract

backgroundWhile several studies have reported the association between 9/11 exposure and cancer risk, cancer survival has not been well studied in the World Trade Center (WTC) exposed population. We examined associations of 9/11-related exposures with mortality in WTC Health Registry enrollees diagnosed with cancer before and after 9/11/2001. PATIENTS AND

methodsThis is a longitudinal cohort study of 5061 enrollees with a first-ever primary invasive cancer diagnosis between 1995 and 2015 and followed through 2016. Based on the timing of first cancer diagnosis, pre-9/11 (n = 634) and post-9/11 (n = 4427) cancer groups were examined separately. 9/11-related exposures included witnessing traumatic events, injury on 9/11, and 9/11-related post-traumatic stress disorder (PTSD). Associations of exposures with all-cause mortality were examined using Cox proportional hazards regression. In the post-9/11 group, cancer-specific mortality was evaluated by enrollee group (WTC rescue/recovery workers vs. non-workers) using Fine and Gray's proportional sub-distribution hazard models, adjusting for baseline covariates, tumor characteristics, and treatment.

resultsIn the pre-9/11 group, 9/11-related exposures were not associated with all-cause mortality. In the post-9/11 group, increased risk of all-cause mortality was associated with PTSD (adjusted HR = 1.35; 95% CI = 1.11-1.65), but not with injury or witnessing traumatic events. Cancer-specific mortality was not statistically significantly associated with 9/11-related exposures. In rescue/recovery workers, increased non-cancer mortality risk was associated with PTSD (aHR = 2.13, 95% CI = 1.13-4.00) and witnessing ≥3 traumatic events (aHR = 2.00, 95% CI = 1.13-3.55).

conclusionsWe did not observe associations between 9/11-related exposures and cancer-specific mortality. Similar to findings in the non-cancer WTC exposed population, PTSD was associated with increased risk of all-cause mortality in cancer patients.

Indexed as

NeoplasmsSeptember 11 Terrorist AttacksTerrorismHumansLongitudinal StudiesRegistries9/11-disastercancermortalityPTSDtrauma

Identifiers

PMID36107389
PMCPMC9883583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.