ArticleAdvances in experimental medicine and biology2022
Nuclear Receptors in Pregnancy and Outcomes: Clinical Perspective.
Article in Advances in experimental medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Rational use of drugs to alleviate adverse outcomes caused by COVID-19 quarantine in women with intrahepatic cholestasis of pregnancy.Frontiers in medicine · 2023Article
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2 authors at 1 institution in 1 country.
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Abstract
Pregnancy is characterised by profound hormonal and metabolic changes in the mother. Both oestrogen and progesterone, along with their respective nuclear receptors, have an important role in maintaining a healthy pregnancy. Equally, other nuclear receptors such as LXR, FXR and the PPARs play important roles in the gradual alterations in metabolism that ensure survival of mother and fetus. Disruptions in nuclear receptor signalling can result in pregnancy disorders such as gestational diabetes mellitus, intrahepatic cholestasis of pregnancy, hypertensive disorders of pregnancy and preterm labour, all of which have both immediate and long-term implications for maternal and fetal health. By reviewing data from human studies and animal models, this chapter will describe the contribution of nuclear receptors to normal pregnancy, their role in gestational disorders and their potential as therapeutic targets.
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