ArticlePlant cell reports2022
Overexpression of the salicylic acid binding protein 2 (SABP2) from tobacco enhances tolerance against Huanglongbing in transgenic citrus.
Article in Plant cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Enhancing cold tolerance through HubZIP6-mediated CBF activation and salicylic acid signaling in pitaya.Molecular horticulture · 2026Article
- Molecular insights into volatile organic compound sensing and signaling in plants.The Plant journal : for cell and molecular biology · 2026Review
- Single-nucleus transcriptomics reveals the cellular immune responses toHorticulture research · 2026Article
- Expression characteristics ofPlant signaling & behavior · 2025Article
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- Dual omics comparison: how Agrobacterium tumefaciens and Agrobacterium rhizogenes modulate gene expression and metabolism in Hypericum perforatum L.BMC genomics · 2025Article
- Bioinformatics analysis of the tomato (Solanum lycopersicum) methylesterase gene family.BMC plant biology · 2025Article
- The Potato StNAC2-StSABP2 Module Enhanced Resistance to Phytophthora infestans Through Activating the Salicylic Acid Pathway.Molecular plant pathology · 2025Article
- "Candidatus Liberibacter asiaticus" Infection Induces Citric Acid Accumulation and Immune Responses Mediated by the Transcription Factor CitPH4.Molecular plant pathology · 2025Article
- Early tolerance mechanisms in citrus: transcriptome and hormone profiling of NPR1-mediated responses toFrontiers in plant science · 2025Article
- Function and Evolution of the Plant MES Family of Methylesterases.Plants (Basel, Switzerland) · 2024Review
- Swords and shields: the war betweenFrontiers in plant science · 2024Review
- Overexpressing CsSABP2 enhances tolerance to Huanglongbing and citrus canker inFrontiers in plant science · 2024Article
- Article
- FourFrontiers in plant science · 2024Article
- An endolysin gene fromHorticulture research · 2023Article
- Comparative transcriptome profiling of susceptible and tolerant citrus species at early and late stage of infection by "Frontiers in plant science · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageOverexpression of the salicylic acid binding protein 2 (SABP2) gene from Tobacco results in enhanced tolerance to Huanglongbing (HLB; citrus greening disease) in transgenic sweet oranges. Huanglongbing (HLB), the most destructive citrus disease, is caused by Candidatus Liberibacter asiaticus (CaLas). Currently, no cure for this disease exists, and all commercially planted cultivars are highly susceptible. Salicylic Acid Binding Protein 2 (SABP2) is a well-characterized protein essential for establishing systemic acquired resistance (SAR) in tobacco. The constitutive over expression of SABP2 from tobacco (NtSABP2) in 'Hamlin' sweet orange resulted in the production of several transgenic lines with variable transcript levels. Transient expression of the NtSABP2-EGFP fusion protein in Nicotiana benthamiana plants demonstrated that NtSABP2 was cytosolic in its subcellular localization. In a long-term field study, we identified a SABP2 transgenic line with significantly reduced HLB symptoms that maintained a consistently low CaLas titer. Transcriptome analysis of this selected transgenic line demonstrated upregulation of several genes related to plant defense and SAR pathways. Genes, such as NPR family genes and those coding for monooxygenases and lipoxygenases, were upregulated in the 35S-NtSABP2 overexpressing line and might be candidates for incorporation into our citrus improvement program.
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