ReviewExpert review of neurotherapeutics2022
Psychotherapeutic treatments for generalized anxiety disorder: cognitive and behavioral therapies, enhancement strategies, and emerging efforts.
Review in Expert review of neurotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- A brief ecological momentary intervention for generalized anxiety disorder: A randomized controlled trial of the worry outcome monitoring app.Journal of anxiety disorders · 2026Trial
- Reducing contrast avoidance in GAD by savoring positive emotions: Outcome and mediation in a randomized controlled trial.Journal of anxiety disorders · 2023Trial
- COVID-19 Worry and Smoking Abstinence Expectancies Among Hispanic Individuals Who Smoke.Journal of racial and ethnic health disparities · 2026Article
- Examining the Contrast Avoidance Model to Understand the Association between Generalized Anxiety Disorder and Sleep Difficulties.The Psychiatric quarterly · 2026Article
- Exploring the role of early maladaptive schemas and intolerance of uncertainty in generalized anxiety disorder.The British journal of clinical psychology · 2026Article
- Comparative Efficacy of Brief Psychoanalytic Psychotherapy and Cognitive Behavioral Therapy for Generalized Anxiety Disorder: A Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Development of a machine learning-based multivariable prediction model for the naturalistic course of generalized anxiety disorder.Journal of anxiety disorders · 2025Article
- Three-Month Durability of Bilateral Two-Level Stellate Ganglion Blocks in Patients with Generalized Anxiety Disorder: A Retrospective Analysis.Brain sciences · 2025Article
- Inter-relationships of depression and anxiety symptoms among widowed and non-widowed older adults: findings from the Chinese Longitudinal Healthy Longevity Survey based on network analysis and propensity score matching.Frontiers in public health · 2025Article
- The relationship between frailty in older adults and anxiety and depression in china: propensity score matching and network analysis.Frontiers in psychiatry · 2025Article
- Incremental validity of the contrast avoidance model: A comparison with intolerance of uncertainty and negative problem orientation.Journal of anxiety disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
introductionGeneralized anxiety disorder (GAD) is common and disabling. Different versions of cognitive behavioral therapy (CBT) have been tested, but no treatment works for everyone. Therefore, researchers have attempted approaches to enhance CBT. AREAS COVERED: The current narrative review examines meta-analyses and individual trials of CBT-based treatments for GAD. We focus on CBT and its cognitive and behavioral components as well as efforts to enhance CBT and its dissemination and generalizability. Enhancement efforts included interpersonal and emotional processing therapy, mindfulness-based CBT, emotion regulation therapy, intolerance of uncertainty therapy, the unified protocol, metacognitive therapy, motivational interviewing, and contrast avoidance targeted treatment. Emerging strategies to enhance dissemination have focused on technologically based treatments. Attempts at generalizability have included examination of efficacy within diverse racial and ethnic groups. EXPERT OPINION: We conclude that CBT is efficacious, and a number of enhancement efforts have shown some promise in improving upon CBT in single trials. However, more research is needed, particularly efforts to determine which enhancements work best for which individuals and what are the mechanisms of change. Furthermore, few technological interventions have been compared to active treatments. Finally, much more attention needs to be paid to ethnic and racial diversity in randomized controlled trials.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.