ArticleInvestigative ophthalmology & visual science2022
Longitudinal Changes in Lens Thickness and Lens Power Among Persistent Non-Myopic and Myopic Children.
Article in Investigative ophthalmology & visual science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 29 citations in OpenAlex.
- Does the Lens Continue to Counteract Axial Elongation in Adults with High Myopia?Ophthalmology science · 2026Article
- Crystalline Lens Tilts Less With Higher Myopia in Children With Limited Age-Related Effect.Translational vision science & technology · 2026Article
- Dynamic relationship between axial length and crystalline lens during myopic refractive development in children: a 5-year cohort study.Eye (London, England) · 2026Article
- Gender and Refractive Error Stratified Ocular Biometry Percentile Curves in Indian School Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Development and Validation of Multinomial Logistic Regression and Machine Learning Algorithms for Identifying Refractive Status in Chinese School Aged Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Molecular and Biomechanical Changes in the Anterior Segment of High Myopic Eyes.Annals of biomedical engineering · 2026Review
- AI-guided personalized predictions on myopia progression and interventions.NPJ digital medicine · 2026Article
- AFrontiers in cell and developmental biology · 2026Article
- Age-related changes in lens thickness in children aged 3-17 years and its association with myopia and ocular biological parameters: a cross-sectional and longitudinal study.Frontiers in pediatrics · 2026Article
- Influence of dynamic changes of ocular biometric parameters on new-onset myopia in Chinese children: a 4-year cohort study.Scientific reports · 2025Article
- Surgical Realignment Reverses Contrast Sensitivity Deficits in Children With Intermittent Exotropia: One-Year Results of a Cohort Study.Investigative ophthalmology & visual science · 2025Article
- In Vivo Brillouin Analysis of Lens Nucleus and Cortex in Adult Myopic Eyes and Their Correlation With Accommodation.Investigative ophthalmology & visual science · 2025Article
- The effect of retinopathy of prematurity on visual acuity, refraction, biometric values, retinal and choroidal thickness in school-aged children.BMC ophthalmology · 2025Article
- Changes in Lens Thickness and Power Before and After Myopia Onset.Investigative ophthalmology & visual science · 2025Article
- Pseudomyopia and cycloplegic changes in young cynomolgus macaques.Molecular vision · 2025Article
- Ocular biometric parameter characteristics and influence on refractive power in Chinese children.International journal of ophthalmology · 2025Article
- Article
- Association Between Myopia and Pupil Diameter in Preschoolers: Evidence from a Machine Learning Approach Based on a Real-World Large-Scale Dataset.Ophthalmology and therapy · 2024Article
- Refraction and ocular biometric parameters in 3-to 6-year-old preschool children : a large-scale population-based study in Chengdu, China.BMC ophthalmology · 2024Article
- Longitudinal changes in crystalline lens thickness and power in children aged 6-12 years old.Eye (London, England) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To assess the longitudinal changes in crystalline lens in persistent non-myopic and myopic children. Methods: Four cohorts of children were recruited from Guangzhou, China, from first year of kindergarten (G0, n = 1129), first year of primary school (G1, n = 1324), fourth year of primary school (G4, n = 1854), and first year of junior high school (G7, n = 867) in 2018 and followed up annually for 2 years. All children received cycloplegic autorefraction and ocular biometry measurement. Children were classified into categories of persistent non-myopia (PNM; spherical equivalent refraction [SER] ≥-0.5 diopter [D] at baseline and during follow-up), persistent myopia (PM; SER <-0.5 D at baseline and during follow-up), or newly developed myopia (NDM: SER ≥-0.5 D at baseline and <-0.5 D during follow-up). Results: The mean (SD) age was 3.69 (0.34) years for children in G0, 6.79 (0.35) years in G1, 9.52 (0.42) years in G4, and 12.56 (0.38) years in G7. A LOWESS plot showed a three-stage pattern of change in lens thickness (LT) in PNM children including a rapid decrease from 3 to 7 years of age and a slower decrease from 7 to 11 years, followed by an increase thereafter. Similar trends were observed in the PM and NDM groups, although there was less change in LT. In contrast, lens power (LP) decreased consistently in all cohorts during the follow-up. No significant changes in LT or LP were observed around myopia onset. Conclusions: The lens showed a three-stage pattern of change in LT, whereas there was continuous loss of LP in children ages 3 to 15 years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.