Evidence map›Paper›PMID 36107024›Full record

ArticleAging2022

Combination of 7-

Yuling Chen, Xiaohong Li, Lei Shi, Pengfei Ma, Wei Wang, Nan Wu, Youlin Gan, Xu Han, Shanshan Huang, Xiaohui Kang and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. MiRNAs: main players of cancer drug resistance target ABC transporters.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yuling ChenCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Xiaohong LiAffiliated Dalian Friendship Hospital of Dalian Medical University, Dalian 116001, China.
Lei ShiCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Pengfei MaCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Wei WangCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Nan WuThe First Affiliated Hospital of Dalian Medical University, Dalian 116023, China.
Youlin GanThe Second Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
Xu HanCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Shanshan HuangCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Xiaohui KangCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Shuxin LiuAffiliated Dalian Municipal Central Hospital of Dalian Medical University, Dalian 116033, China.
Yuhong ZhenCollege of Pharmacy, Dalian Medical University, Dalian 116044, China.
Dalian Medical University · CNDalian Municipal Central Hospital · CNSecond Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although there are a lot of chemical drugs to treat breast cancer, increasing drug resistance of cancer cells has strongly hindered the effectiveness of chemotherapy. ATP-binding cassette transporters represented by P-glycoprotein (P-gp), multidrug resistance associated protein 1 (MRP1) and breast cancer resistance protein (BCRP) play an important role in drug resistance. This study aims to investigate the effect of 7-

Indexed as

Breast NeoplasmsMicroRNAsAnimalsATP-Binding Cassette, Sub-Family C ProteinsATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 1ATP Binding Cassette Transporter, Subfamily G, Member 2Cell Line, TumorDoxorubicinDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticHumansMiceMice, NudeNeoplasm Proteins7-O-geranylquercetinATP-Binding Cassette, Sub-Family C ProteinsATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 1ATP Binding Cassette Transporter, Subfamily G, Member 2DoxorubicinMicroRNAsMIRN326 microRNA, humanMIRN451 microRNA, humanMirn451 microRNA, mouseNeoplasm ProteinsQuercetin7-O-geranylquercetinAdriamycindrug resistancemicroRNA-451P-glycoprotein

Identifiers

PMID36107024
PMCPMC9512499
OpenAlexW4295789858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.