Evidence map›Paper›PMID 36106767›Full record

ArticleJournal of the American Chemical Society2022

Overcoming Limitations in Decarboxylative Arylation via Ag-Ni Electrocatalysis.

Maximilian D Palkowitz, Gabriele Laudadio, Simon Kolb, Jin Choi, Martins S Oderinde, Tamara El-Hayek Ewing, Philippe N Bolduc, TeYu Chen, Hao Zhang, Peter T W Cheng and 17 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Cross-Electrophile Coupling ofJournal of the American Chemical Society · 2026
    Article
  8. Article
  9. Dibromocarbene addition to bicyclo[1.1.0]butanes: A facile route to substituted bicyclo[1.1.1]pentanes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Maximilian D PalkowitzDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0002-3651-5175
Gabriele LaudadioDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0002-2749-8393
Simon KolbDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0001-6352-4619
Jin ChoiDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0001-5759-8419
Martins S OderindeBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.
Tamara El-Hayek EwingDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Philippe N BolducBiogen Inc., 225 Binney Street, Cambridge, Massachusetts 02142, United States.ORCID 0000-0001-8726-4364
TeYu ChenBiogen Inc., 225 Binney Street, Cambridge, Massachusetts 02142, United States.
Hao ZhangBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.
Peter T W ChengBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.ORCID 0000-0002-6289-8341
Benxiang ZhangDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
Michael D MandlerBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.ORCID 0000-0003-4681-7473
Vanna D BlasczakBiogen Inc., 225 Binney Street, Cambridge, Massachusetts 02142, United States.
Jeremy M RichterBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.ORCID 0000-0002-8313-7154
Michael R CollinsOncology Medicinal Chemistry Department, Pfizer Pharmaceuticals, 10770 Science Center Drive, San Diego, California 92121, United States.
Ryan L SchioldagerOncology Medicinal Chemistry Department, Pfizer Pharmaceuticals, 10770 Science Center Drive, San Diego, California 92121, United States.
Martin BravoOncology Medicinal Chemistry Department, Pfizer Pharmaceuticals, 10770 Science Center Drive, San Diego, California 92121, United States.
T G Murali DharBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.ORCID 0000-0003-0738-1021
Benjamin VokitsBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.
Yeheng ZhuBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.
Pierre-Georges EcheverriaMinakem Recherche, 145 Chemin des Lilas, Beuvry-La-Forêt 59310, France.ORCID 0000-0001-9938-5083
Michael A PossBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.ORCID 0000-0002-2423-8553
Scott A ShawBristol Myers Squibb Research and Development, P.O. Box 4000, Princeton, New Jersey 08534, United States.
Sebastian ClementsonResearch and Early Development, LEO Pharma A/S, 2750 Ballerup, Denmark.
Nadia Nasser PetersenResearch and Early Development, LEO Pharma A/S, 2750 Ballerup, Denmark.ORCID 0000-0002-8595-3497
Pavel K MykhailiukEnamine Ltd., Chervonotkatska 60, 02094 Kyiv, Ukraine.ORCID 0000-0003-1821-9011
Phil S BaranDepartment of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.ORCID 0000-0001-9193-9053

Funding

Scalable Synthesis and New Bond DisconnectionsR35GM118176 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI BARAN, PHIL S · 2016 to 2025
$11.5M
NIGMS NIH HHS R35 GM118176
6 · The paper itself

Abstract

A useful protocol for achieving decarboxylative cross-coupling (DCC) of redox-active esters (RAE, isolated or generated in situ) and halo(hetero)arenes is reported. This pragmatically focused study employs a unique Ag-Ni electrocatalytic platform to overcome numerous limitations that have plagued this strategically powerful transformation. In its optimized form, coupling partners can be combined in a surprisingly simple way: open to the air, using technical-grade solvents, an inexpensive ligand and Ni source, and substoichiometric AgNO

Indexed as

EstersCatalysisLigandsOxidation-ReductionSolventsEstersLigandsSolvents

Identifiers

PMID36106767
PMCPMC9805175

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.