ArticleDevelopmental medicine and child neurology2023
Preterm postnatal complications and risk of attention-deficit/hyperactivity disorder.
Article in Developmental medicine and child neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 16 citations in OpenAlex.
- Neurodevelopmental risks of late-preterm and early-term births: a population-based study from Finland.BMJ public health · 2026Article
- Preterm Birth and the Emergence of ADHD Symptoms: A Review of Recent Evidence.Medicina (Kaunas, Lithuania) · 2025Review
- The Premature Infants' Gut Microbiota Assembly and Neurodevelopment (PIGMAN) Cohort Study: Protocol for a Prospective, Longitudinal Cohort Study.Children (Basel, Switzerland) · 2025Article
- Prenatal Cocaine Exposure, Perinatal Risks, and Mediators to Preadolescent Attention Deficit Hyperactivity Disorder (ADHD).Children (Basel, Switzerland) · 2025Article
- Association of premature birth and maternal education level on attention deficit hyperactivity disorder in children: A meta-analysis.World journal of psychiatry · 2024Article
- Early dental visit affects dental treatment in Korean preschool children born preterm: a nationwide population-based study.Scientific reports · 2024Article
- Correlational Insights into Attention-Deficit/Hyperactivity Disorder in Lebanon.International journal of environmental research and public health · 2024Article
- Children with a history of both maternal immune activation and prematurity are not at increased risk of ADHD symptoms.European child & adolescent psychiatry · 2024Article
- Mediators of attention-deficit/hyperactivity disorder risk in individuals born preterm.Developmental medicine and child neurology · 2023Article
- Preterm Birth Causes Decreased Postnatal Neurogenesis: A Novel Mechanism Underlying Adverse Neurodevelopmental Outcomes.Pediatrics international : official journal of the Japan Pediatric SocietyReview
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10 authors at 6 institutions in 5 countries.
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No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the association between the risk of attention-deficit/hyperactivity disorder (ADHD) and preterm birth and determine how postnatal complications in children born preterm is associated with the risk of ADHD.
methodThis population-based cohort study used data from the Hong Kong electronic medical records. We followed 359 614 children (48% female; 6-17 years old, mean 11 years 7 months, SD 3 years 2 months) born in public hospitals in Hong Kong from 1st January 2004 to 31st December 2014 and collected medical records and demographic details for mothers and children until 11th November 2020.
resultsThe risk of ADHD was 4.0% in children born at term and 5.1% in children born preterm. The odds ratio for ADHD was 2.08 (95% confidence interval [CI] 1.64-2.64) for children born extremely preterm, 1.64 (95% CI 1.46-1.85) for children born very preterm, and 1.15 (95% CI 1.08-1.23) for children born late preterm. Among preterm postnatal complications, only early respiratory disease, retinopathy of prematurity (ROP), and intraventricular haemorrhage were significant predictors of ADHD after controlling for preterm birth, other risk factors, and sociodemographic variables. The excess risk of ADHD among children born very preterm or late preterm could be partly explained by respiratory disease. ROP partially mediated the risk of ADHD in children born very preterm.
interpretationChildren born preterm in all subcategories, from extremely preterm to late preterm, have increased risk of ADHD. Early respiratory infection partially mediates the risk of ADHD in children born preterm.
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