Evidence map›Paper›PMID 36106418›Full record

ArticlePhysiological reports2022

Heart rate variability during head-up tilt shows inter-individual differences among healthy individuals of extreme Prakriti types.

Ritu Rani, Prathiban Rengarajan, Tavpritesh Sethi, Bharat Krushna Khuntia, Arvind Kumar, Deep Shikha Punera, Deepika Singh, Bhushan Girase, Ankita Shrivastava, Sanjay K Juvekar and 4 more

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. A scoping review of clinicalFrontiers in medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Ritu RaniCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR-Institute of Genomics & Integrative Biology, Delhi, India.
Prathiban RengarajanDepartment of Physiology, All India Institute of Medical Sciences, New Delhi, India.
Tavpritesh SethiGenomics and Molecular Medicine, CSIR-Institute of Genomics & Integrative Biology, Delhi, India.
Bharat Krushna KhuntiaCSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRough Ayurgenomics) CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Arvind KumarCSIR's Ayurgenomics Unit-TRISUTRA (Translational Research and Innovative Science ThRough Ayurgenomics) CSIR-Institute of Genomics and Integrative Biology, New Delhi, India.
Deep Shikha PuneraCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR-Institute of Genomics & Integrative Biology, Delhi, India.
Deepika SinghCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR-Institute of Genomics & Integrative Biology, Delhi, India.
Bhushan GiraseVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Ankita ShrivastavaVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Sanjay K JuvekarVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Bala PesalaIndian Institute of Technology Jodhpur, Rajasthan, India.
Mitali MukerjiCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR-Institute of Genomics & Integrative Biology, Delhi, India.
Kishore Kumar DeepakDepartment of Physiology, All India Institute of Medical Sciences, New Delhi, India.
Bhavana PrasherCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR-Institute of Genomics & Integrative Biology, Delhi, India.ORCID 0000-0003-4185-4400
Institute of Genomics and Integrative Biology · INDr. D. Y. Patil Medical College, Hospital and Research Centre · INAll India Institute of Medical Sciences · INIndian Institute of Technology Jodhpur · INIndraprastha Institute of Information Technology Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autonomic modulation is critical during various physiological activities, including orthostatic stimuli and primarily evaluated by heart rate variability (HRV). Orthostatic stress affects people differently suggesting the possibility of identification of predisposed groups to autonomic dysfunction-related disorders in a healthy state. One way to understand this kind of variability is by using Ayurvedic approach that classifies healthy individuals into Prakriti types based on clinical phenotypes. To this end, we explored the differential response to orthostatic stress in different Prakriti types using HRV. HRV was measured in 379 subjects(Vata = 97, Pitta = 68, Kapha = 68, and Mixed Prakriti = 146) from two geographical regions(Vadu and Delhi NCR) for 5 min supine (baseline), 3 min head-up-tilt (HUT) at 60°, and 5 min resupine. We observed that Kapha group had lower baseline HRV than other two groups, although not statistically significant. The relative change (%Δ

Indexed as

Autonomic Nervous System DiseasesIndividualityAutonomic Nervous SystemHeartHeart RateHumansPostureautonomic nervous systemAyurgenomicsAyurvedahead-up tiltheart rate variabilityorthostatic stressPrakriti

Identifiers

PMID36106418
PMCPMC9475339
OpenAlexW4295898646

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.