Evidence map›Paper›PMID 36106375›Full record

Observational studyActa obstetricia et gynecologica Scandinavica2022

The impact of diagnosed fetal anomaly, diagnostic severity and prognostic ambiguity on parental depression and traumatic stress: a prospective longitudinal cohort study.

Aurora Oftedal, Mona Bekkhus, Guttorm Nils Haugen, Nikolai Olavi Czajkowski, Anne Kaasen

Abstract readObservational Study
In one paragraph

Observational study in Acta obstetricia et gynecologica Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Psychological Support in Prenatal Diagnosis: The Parental Perspective.Journal of clinical psychology in medical settings · 2026
    Article
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  5. Observational
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  9. Family dynamics after diagnosis and surgical treatment of myelomeningocele: using telemedicine as a complementary tool.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
  10. Article
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  17. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aurora OftedalFaculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.ORCID 0000-0003-1598-8771
Mona BekkhusDepartment of Psychology, Promenta Research Center, University of Oslo, Oslo, Norway.
Guttorm Nils HaugenDivision of Obstetrics and Gynecology, Oslo University Hospital, Oslo, Norway.
Nikolai Olavi CzajkowskiDepartment of Psychology, Promenta Research Center, University of Oslo, Oslo, Norway.
Anne KaasenFaculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.ORCID 0000-0001-9291-0105

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe detection of a fetal anomaly during routine obstetric ultrasound is a potentially traumatic experience. The aim of this study is to examine longitudinally the impact of diagnosis of fetal anomaly on symptoms of depression and traumatic stress among mothers and fathers, and to examine how variations in psychological adjustment relate to diagnostic severity and prognostic ambiguity. MATERIAL AND

methodsIn this prospective observational study conducted at a tertiary perinatal referral center, 81 mothers and 69 fathers with ultrasound findings of fetal anomaly completed the Edinburgh Postnatal Depression Scale (EPDS) and Impact of Events Scale (IES) at four time points in pregnancy (T1-T4) and 6 weeks after birth (T5). We compared this with depression and traumatic stress in a sample of non-affected parents (n = 110 mothers, 98 fathers).

resultsLinear mixed effects models indicated that parents who received a diagnosis of fetal anomaly experienced higher levels of depression and traumatic stress over time, compared with non-affected parents. Depression: mean difference mothers = 4.46 ± 0.47, fathers = 2.80 ± 0.42. Traumatic stress: mean difference mothers = 20.04 ± 2.13, fathers = 12.66 ± 1.74. Parents with a more severe diagnosis experienced elevated symptoms compared with parents with a less severe diagnosis. Among mothers, prognostic ambiguity and changes in the anticipated diagnosis after birth were also associated with increased distress, regardless of whether the change was for the better or worse.

conclusionsDiagnosis of fetal anomaly increases risk of depression and traumatic stress in expectant mothers and fathers, both acutely and over time.

Indexed as

Depression, PostpartumFathersCohort StudiesDepressionFemaleHumansLongitudinal StudiesMaleMothersParentsPregnancyPrognosisProspective StudiesStress, Psychologicalcongenital malformationdepressionpostpartumpregnancyprenatal diagnosispsychological distresstraumatic stress

Identifiers

PMID36106375
PMCPMC9812208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.