Evidence map›Paper›PMID 36106285›Full record

ArticleCureus2022

Stellate Ganglion Block for Anosmia and Dysgeusia Due to Long COVID.

Gaurav Chauhan, Aman Upadhyay, Suchit Khanduja, Trent Emerick

Registry-linked trialOpen access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06253806 (Stellate Ganglion Block for the Treatment of COVID-19-Induced Parosmia), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06253806 phase2completednot on this mapstarted 2023, after this paper: background citation

Stellate Ganglion Block for the Treatment of COVID-19-Induced Parosmia: Double-Blinded, Placebo-Controlled Randomized Clinical Trial

TypeinterventionalSponsorWashington University School of MedicineRan2023 to 2024Enrolled48ConditionsCOVID-19-Induced ParosmiaArmsStellate Ganglion Block, Placebo Sham Injection
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Review
  3. Parosmia: Pathophysiology and Management.Current allergy and asthma reports · 2025
    Review
  4. Long-term olfactory loss post-COVID-19: Pathobiology and potential therapeutic strategies.World journal of otorhinolaryngology - head and neck surgery · 2024
    Review
  5. Clinical studies in COVID-related olfactory disorders: Review of an institutional experience.World journal of otorhinolaryngology - head and neck surgery · 2024
    Article
  6. Musculoskeletal and Neuropathic Pain in COVID-19.Diagnostics (Basel, Switzerland) · 2024
    Review
  7. Review
  8. Stellate Ganglion Block for the Treatment of COVID-19-Induced Olfactory Dysfunction: A Prospective Pilot Study.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Gaurav ChauhanAnesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center Presbyterian, Pittsburgh, USA.
Aman UpadhyayPain Management, Pain Clinic of Michigan, Rochester Hills, USA.
Suchit KhandujaAnesthesiology, Beaumont Hospital, Southfield, USA.
Trent EmerickPain Medicine, University of Pittsburgh Medical Center, Pittsburgh, USA.
Pain Management Institute · USThe Beaumont Hospital · GBUniversity of Pittsburgh Medical Center · USUPMC Presbyterian · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anosmia and parosmia refer to the loss or dysfunction of smell, respectively. Dysgeusia refers to taste disturbance. The coronavirus disease 2019 (COVID-19) pandemic and the subsequent phenomenon of Long COVID syndrome have been associated with an increased incidence of anosmia and dysgeusia. Smell and taste disturbances associated with COVID-19 are usually self-limiting but can persist for longer periods in some cases. Imbalances of the autonomic nervous system, especially dysregulation of the sympathetic system, are implicated in the persistence of anosmia and dysgeusia post-COVID-19 infection. Stellate ganglion block (SGB) can diminish the increased sympathetic activity and potentially resolve anosmia and dysgeusia occurring due to Long COVID. The authors report the successful resolution of persistent anosmia and dysgeusia due to Long COVID in a female patient after she underwent SGB.

Indexed as

anosmiacovid-19dysautonomiadysgeusialong-covid

Identifiers

PMID36106285
PMCPMC9450932
OpenAlexW4295540536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.