ReviewTemperature (Austin, Tex.)2022
Human vulnerability and variability in the cold: Establishing individual risks for cold weather injuries.
Review in Temperature (Austin, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Using Organoids to Unlock the Potential of Human Torpor for Spaceflight.Current stem cell reports · 2026Article
- Intersections of climate and society: cold stress vulnerability in Northern Norway.International journal of biometeorology · 2026Article
- Article
- Cold-induced vasodilation: A meta-analysis.Temperature (Austin, Tex.) · 2026Review
- Cold operational readiness in the military: from science to practice.BMJ military health · 2025Review
- Assessing bias in measuring power outage exposure with simulations.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Impact of rapid temperature fluctuations on acute stroke risk: a nationwide case-crossover study from 2001 to 2020.The Lancet regional health. Western Pacific · 2025Article
- Cold weather operations: Preventive strategies in a military context.Temperature (Austin, Tex.) · 2025Review
- Integrated effects of cold acclimation: physiological mechanisms, psychological adaptations, and potential applications.Frontiers in physiology · 2025Review
- Thermal physiology of open water wetsuited swimming: A cohort study.Temperature (Austin, Tex.) · 2025Article
- Global warming, Arctic exploration, and imprisonment of political opponents: Temperature is ubiquitous.Temperature (Austin, Tex.) · 2025Article
- Article
- Climate crisis risks to elderly health: strategies for effective promotion and response.Health promotion international · 2024Review
- Cold-induced vasodilation during sequential immersions of the hand.European journal of applied physiology · 2024Article
- We are all exposed, but some are more exposed than others.International journal of circumpolar health · 2023Article
- Training videos to prevent cold weather injuries.International journal of circumpolar health · 2023Article
- Extremity cooling during an arctic diving training exercise.International journal of circumpolar health · 2023Article
- Nonoptimum Temperatures Are More Closely Associated With Fatal Myocardial Infarction Than With Nonfatal Events.The Canadian journal of cardiology · 2023Article
- To the extreme! How biological anthropology can inform exercise physiology in extreme environments.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2023Review
- Peripheral sensory function in non-freezing cold injury patients and matched controls.Experimental physiology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human tolerance to cold environments is extremely limited and responses between individuals is highly variable. Such physiological and morphological predispositions place them at high risk of developing cold weather injuries [CWI; including hypothermia and/or non-freezing (NFCI) and freezing cold injuries (FCI)]. The present manuscript highlights current knowledge on the vulnerability and variability of human cold responses and associated risks of developing CWI. This review 1) defines and categorizes cold stress and CWI, 2) presents cold defense mechanisms including biological adaptations, acute responses and acclimatization/acclimation and, 3) proposes mitigation strategies for CWI. This body of evidence clearly indicates that all humans are at risk of developing CWI without adequate knowledge and protective equipment. In addition, we show that while body mass plays a key role in mitigating risks of hypothermia between individuals and populations, NFCI and FCI depend mainly on changes in peripheral blood flow and associated decrease in skin temperature. Clearly, understanding the large interindividual variability in morphology, insulation, and metabolism is essential to reduce potential risks for CWI between and within populations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.