Evidence map›Paper›PMID 36106146›Full record

ArticleTemperature (Austin, Tex.)2022

No protective benefits of low dose acute L-glutamine supplementation on small intestinal permeability, epithelial injury and bacterial translocation biomarkers in response to subclinical exertional-heat stress: A randomized cross-over trial.

Henry B Ogden, Joanne L Fallowfield, Robert B Child, Glen Davison, Simon C Fleming, Simon K Delves, Alison Millyard, Caroline S Westwood, Joseph D Layden

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Temperature (Austin, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Henry B OgdenSchool of Sport, Health and Wellbeing, Plymouth MARJON University, Plymouth, UK.ORCID https://orcid.org/0000-0001-7827-0922
Joanne L FallowfieldEnvironmental Medicine and Science Division, Institute of Naval Medicine, Alverstoke, UK.
Robert B ChildSchool of Chemical Engineering, University of Birmingham, Birmingham, UK.
Glen DavisonEndurance Research Group, School of Sport and Exercise Sciences, University of Kent, Chatham Maritime, UK.ORCID https://orcid.org/0000-0003-4340-0074
Simon C FlemingDepartment of Clinical Chemistry, Royal Cornwall NHS Trust, Truro, UK.
Simon K DelvesEnvironmental Medicine and Science Division, Institute of Naval Medicine, Alverstoke, UK.
Alison MillyardSchool of Sport, Health and Wellbeing, Plymouth MARJON University, Plymouth, UK.
Caroline S WestwoodSchool of Sport, Health and Wellbeing, Plymouth MARJON University, Plymouth, UK.
Joseph D LaydenSchool of Sport, Health and Wellbeing, Plymouth MARJON University, Plymouth, UK.
Plymouth Marjon University · GBMedway School of Pharmacy · GBRoyal Cornwall Hospital Trust · GBUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exertional heat stress disrupts gastrointestinal permeability and, through subsequent bacterial translocation, can result in potentially fatal exertional heat stroke. Glutamine supplementation is a potential countermeasure although previously validated doses are not universally well tolerated. Ten males completed two 80-minute subclinical exertional heat stress tests (EHSTs) following either glutamine (0.3 g kg FFM

Indexed as

endotoxinexerciseGutheat strokeI-FABPmicrobiota

Identifiers

PMID36106146
PMCPMC9467553
OpenAlexW4200514414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.